Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3896617 | 1.00 | ALDH1A1 (0.45) | ALDH1A1GLATDP1L3MBTL1TP53 | |
| SCHEMBL3899604 | 1.00 | ALDH1A1 (0.45) | ALDH1A1GLATDP1L3MBTL1TP53 | |
| SCHEMBL7129045 | 0.98 | ALDH1A1 (0.46) | ALDH1A1GLATDP1L3MBTL1TP53 | |
| SCHEMBL3900147 | 0.95 | ALDH1A1 (0.46) | ALDH1A1GLATDP1L3MBTL1TP53 | |
| SCHEMBL7123430 | 0.93 | ALDH1A1 (0.47) | ALDH1A1GLATDP1L3MBTL1TP53 | |
| SCHEMBL14199651 | 0.87 | ALDH1A1 (0.46) | ALDH1A1GLATDP1L3MBTL1TP53 | |
| SCHEMBL1129712 | 0.84 | ALDH1A1 (0.64) | ALDH1A1GLATDP1TP53CYP1A2 | |
| SCHEMBL14199653 | 0.83 | DRD4 (0.51) | ALDH1A1GLATDP1L3MBTL1TP53 | |
| SCHEMBL1312619 | 0.82 | ALDH1A1 (0.46) | ALDH1A1GLATDP1TP53CYP3A4 | |
| SCHEMBL6305830 | 0.82 | ALDH1A1 (0.46) | ALDH1A1GLATDP1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781238-B1 | DENTAL COMPOSITIONS CONTAINING OXIRANE MONOMERS | 3M INNOVATIVE PROPERTIES CO (US) | 2009-03-18 | — | — | EP | disclosed |
| US-20080085494-A1 | Dental Compositions Containing Oxirane Monomers | 3M ESPE AG (DE) | 2008-04-10 | — | — | US | disclosed |
| US-20080085494-A1 | Dental Compositions Containing Oxirane Monomers | 3M ESPE AG (DE) | 2008-04-10 | — | — | US | disclosed |
| EP-1781238-A1 | DENTAL COMPOSITIONS CONTAINING OXIRANE MONOMERS | 3M Innovative Properties Company (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006019797-A1 | DENTAL COMPOSITIONS CONTAINING OXIRANE MONOMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-02-23 | — | — | WO | disclosed |