SCHEMBL3909306

SCHEMBL3909306

CO[Si](OC)(OC)OC(C)=O.[LiH]

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3912403 0.97 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL3912674 0.94 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL487443 0.91 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL487271 0.91 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL49515 0.81 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL15828933 0.79 HSD17B10 (0.40) ALDH1A1
SCHEMBL7840079 0.78 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL9664185 0.75 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL3912225 0.74 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL371452 0.72 ALDH1A1 (0.55) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 EP disclosed