Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CNR1 | P21554 | 2/20 | 0.57 |
| ▸ | CNR2 | P34972 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968836 | 0.87 | NPSR1 (0.58) | ALDH1A1NPSR1TP53ALOX15MAPK1 | |
| SCHEMBL7342866 | 0.85 | CNR1 (0.60) | ALDH1A1NPSR1TP53ALOX15MAPK1 | |
| SCHEMBL3909939 | 0.80 | NPSR1 (0.48) | ALDH1A1NPSR1TP53ALOX15MAPK1 | |
| SCHEMBL3280160 | 0.77 | POLB (0.54) | ALDH1A1NPSR1TP53ALOX15MAPK1 | |
| SCHEMBL3699604 | 0.77 | POLB (0.54) | ALDH1A1NPSR1TP53ALOX15MAPK1 | |
| SCHEMBL6954047 | 0.76 | ALDH1A1 (0.54) | ALDH1A1NPSR1TP53ALOX15MAPK1 | |
| SCHEMBL2567557 | 0.76 | MAPT (0.48) | ALDH1A1NPSR1TP53ALOX15MAPK1 | |
| SCHEMBL14538165 | 0.76 | MAPK1 (0.49) | ALDH1A1NPSR1TP53ALOX15MAPK1 | |
| SCHEMBL28386907 | 0.76 | KDM4E (0.59) | ALDH1A1NPSR1TP53ALOX15MAPK1 | |
| SCHEMBL9303072 | 0.75 | ALDH1A1 (0.73) | ALDH1A1NPSR1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579487-B2 | Process for making N-sulfonated-amino acid derivatives | MERCK & CO., INC. (US) | 2009-08-25 | — | — | US | disclosed |
| EP-1747212-A4 | PROCESS FOR MAKING N-SULFONATED-AMINO ACID DERIVATIVES | MERCK & CO INC (US) | 2009-03-25 | — | — | EP | disclosed |
| US-20070219382-A1 | Process For Making N-Sulfonated-Amino Acid Derivatives | MERCK SHARP & DOHME CORP. | 2007-09-20 | — | — | US | disclosed |
| EP-1747212-A2 | PROCESS FOR MAKING N-SULFONATED-AMINO ACID DERIVATIVES | Merck and Co., Inc. (US) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005118529-A2 | PROCESS FOR MAKING N-SULFONATED-AMINO ACID DERIVATIVES | MERCK & CO., INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| CN-1152880-A | Method for diagnostic image analysis using metal complexes of nitrogen-containing macrocyclic ligands | MONSANTO CO (US) | 1997-06-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219382-A1 | Process For Making N-Sulfonated-Amino Acid Derivatives | ANTXR2, STS, ASNS | ALDH1A1 2796/4885NPSR1 633/4885TP53 3556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.