Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960165 | 0.99 | ALDH1A1 (0.52) | ALDH1A1NPSR1TP53ALOX15MAPK1 | |
| SCHEMBL6965063 | 0.88 | KMT2A (0.50) | ALDH1A1NPSR1TP53ALOX15MAPK1 | |
| SCHEMBL6963809 | 0.85 | CNR1 (0.53) | ALDH1A1NPSR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL6963632 | 0.85 | NPSR1 (0.47) | ALDH1A1NPSR1TP53ALOX15MAPK1 | |
| SCHEMBL6965348 | 0.81 | SLC6A2 (0.52) | ALDH1A1NPSR1GAAHTT | |
| SCHEMBL3280160 | 0.76 | POLB (0.54) | ALDH1A1NPSR1TP53ALOX15MAPK1 | |
| SCHEMBL3909934 | 0.76 | ALDH1A1 (0.67) | ALDH1A1NPSR1TP53ALOX15MAPK1 | |
| SCHEMBL3699604 | 0.76 | POLB (0.54) | ALDH1A1NPSR1TP53ALOX15MAPK1 | |
| SCHEMBL9303072 | 0.74 | ALDH1A1 (0.73) | ALDH1A1NPSR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL11116465 | 0.73 | CNR1 (0.50) | ALDH1A1NPSR1TP53ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | claimed |
| CN-101460494-A | Process for production of 4-substituted azetidinone derivatives | KANEGAFUCHI CHEMICAL IND (JP) | 2009-06-17 | — | — | CN | disclosed |
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0974582-A1 | Process for the preparation of 4-substituted azetidinone derivatives | Takasago International Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |