SCHEMBL3910096

SCHEMBL3910096

CCO[Si](C)(CCCC1CCCN1)OCC

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.35
CHRNB2 P17787 4/20 0.35
CHRNB4 P30926 4/20 0.35
CHRNA3 P32297 4/20 0.35
CHRNA5 P30532 1/20 0.35
CHRNA4 P43681 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3911375 0.95 HRH3 (0.40) HRH3CHRNB2CHRNB4CHRNA3CHRNA5
SCHEMBL3919752 0.90 CHRNA3 (0.36) HRH3CHRNB2CHRNB4CHRNA3CHRNA5
SCHEMBL3919541 0.85 HRH3 (0.38) HRH3CHRNB2CHRNB4CHRNA3CHRNA5
SCHEMBL3912530 0.85 HRH3 (0.36) HRH3CHRNB2CHRNB4CHRNA3CHRNA5
SCHEMBL16714750 0.83 HRH3 (0.40) HRH3CHRNB2CHRNB4CHRNA3CHRNA5
SCHEMBL3910872 0.81 HRH3 (0.41) HRH3
SCHEMBL23175032 0.79 HRH3 (0.34) HRH3
SCHEMBL3912128 0.79 HRH3 (0.42) HRH3CHRNB2CHRNB4CHRNA3CHRNA5
SCHEMBL16714732 0.78 MKNK1 (0.30)
SCHEMBL3918912 0.78 CHRNB2 (0.35) HRH3CHRNB2CHRNB4CHRNA3CHRNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed