SCHEMBL3910207

SCHEMBL3910207

CCO[Si](CCCC1CCNCC1)(OCC)OCC

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GNAO1 P09471 3/20 0.37
HRH3 Q9Y5N1 2/20 0.37
GNAI3 P08754 2/20 0.33
GNAI1 P63096 2/20 0.33
FAAH O00519 1/20 0.33
ITGB3 P05106 3/20 0.32
ITGA2B P08514 3/20 0.32
CYP1A2 P05177 1/20 0.31
TPSAB1 Q15661 1/20 0.31
TPSD1 Q9BZJ3 1/20 0.31
TPSG1 Q9NRR2 1/20 0.31
SLC6A4 P31645 1/20 0.31
TLR7 Q9NYK1 5/20 0.31
NAMPT P43490 1/20 0.31
AVPR2 P30518 1/20 0.30
AVPR1A P37288 1/20 0.30
TLR8 Q9NR97 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3909897 0.93 GNAO1 (0.36) GNAO1HRH3GNAI3GNAI1
SCHEMBL3915153 0.90 SLC6A1 (0.33) HRH3
SCHEMBL3919939 0.84 GNAO1 (0.36) GNAO1HRH3GNAI3GNAI1FAAH
SCHEMBL23521408 0.83 CYP1A2 (0.48) CYP1A2
SCHEMBL3909903 0.82 SLC6A1 (0.35) HRH3
SCHEMBL3987790 0.81 HRH3 (0.39) GNAO1HRH3GNAI3GNAI1FAAH
SCHEMBL17766148 0.81 CYP1A2 (0.52) CYP1A2TLR7
SCHEMBL16714788 0.80 HRH3 (0.43) HRH3TLR7
SCHEMBL3918001 0.80 GNAO1 (0.35) GNAO1HRH3GNAI3GNAI1FAAH
SCHEMBL7063450 0.78 CYP1A2 (0.30) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed