Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907315 | 0.83 | GAA (0.43) | MTNR1AOPRM1OPRL1GAACASR | |
| SCHEMBL10961720 | 0.82 | SLC6A4 (0.54) | SLC6A4EPHX2ALDH1A1CTSGCYP2C9 | |
| SCHEMBL3903074 | 0.82 | CASR (0.50) | HPGDOPRM1OPRL1CASR | |
| SCHEMBL3906138 | 0.80 | CASR (0.46) | HPGDOPRM1OPRL1CASR | |
| SCHEMBL3908324 | 0.80 | MEN1 (0.46) | ALDH1A1MTNR1AHPGDHTTOPRM1 | |
| SCHEMBL3903167 | 0.77 | OPRM1 (0.44) | EPHX2CYP2C9CYP2C19HTTOPRM1 | |
| SCHEMBL3911825 | 0.77 | CNR1 (0.50) | ALDH1A1MTNR1AOPRM1OPRD1OPRK1 | |
| SCHEMBL3906098 | 0.76 | OPRL1 (0.56) | OPRM1OPRL1CASR | |
| SCHEMBL3916716 | 0.76 | CASR (0.53) | ALDH1A1MTNR1ACYP2C9CYP2C19OPRM1 | |
| SCHEMBL3908089 | 0.76 | CASR (0.53) | OPRL1CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |