Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.51 |
| ▸ | HPN | P05981 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.49 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.49 |
| ▸ | CCR8 | P51685 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14132161 | 0.96 | F10 (0.67) | F10CHRM2CHRM1CHRM4HPN | |
| Trifluoroacetic Acid SCHEMBL3974775 | 0.88 | F10 (0.64) | F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL3902693 | 0.86 | F10 (0.64) | F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL3968850 | 0.85 | F10 (0.61) | F10PRSS1PRSS2PRSS3ST14 | |
| Trifluoroacetic Acid SCHEMBL3970578 | 0.85 | F10 (0.61) | F10PRSS1 | |
| Trifluoroacetic Acid SCHEMBL3910396 | 0.83 | F10 (0.61) | F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL3973028 | 0.83 | F10 (0.90) | F10 | |
| SCHEMBL14131982 | 0.83 | F10 (0.69) | F10PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL3898005 | 0.82 | F10 (0.58) | F10PRSS1PRSS2PRSS3 | |
| SCHEMBL3971725 | 0.80 | CHRM4 (0.65) | CHRM2CHRM1CHRM4CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |