Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778389 | 0.84 | SLC6A4 (0.58) | SLC6A4AURKARPS6KB1SLC6A3EPHX2 | |
| SCHEMBL23002585 | 0.79 | MAOA (0.61) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL2834145 | 0.79 | SLC6A4 (0.71) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3932199 | 0.78 | SLC6A4 (0.57) | SLC6A4SLC6A3EPHX2 | |
| SCHEMBL3518765 | 0.78 | SLC6A4 (0.69) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3523695 | 0.76 | SLC6A4 (1.00) | SLC6A4AURKARPS6KB1SLC6A3SLC6A2 | |
| SCHEMBL3516539 | 0.76 | SLC6A4 (1.00) | SLC6A4AURKARPS6KB1SLC6A3SLC6A2 | |
| SCHEMBL13510872 | 0.75 | SLC6A4 (0.66) | SLC6A4AURKARPS6KB1SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL2783390 | 0.74 | SLC6A4 (0.64) | SLC6A4AURKARPS6KB1SLC6A3SLC6A2 | |
| SCHEMBL3132000 | 0.73 | SLC6A4 (0.64) | SLC6A4SLC6A3EPHX2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029592-A1 | PHARMACEUTICAL COMPOUNDS | Astex Therapeutics Limited (GB) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007125325-A1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2007-11-08 | — | — | WO | disclosed |