Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.68 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4228186 | 0.87 | PRKDC (0.64) | PRKDCLCKFYNALDH1A1KDM4E | |
| SCHEMBL29956928 | 0.82 | ALDH1A1 (0.62) | PRKDCLCKFYNALDH1A1KDM4E | |
| SCHEMBL4367355 | 0.82 | ALDH1A1 (0.62) | PRKDCLCKFYNALDH1A1KDM4E | |
| SCHEMBL3910995 | 0.82 | KDM4E (0.52) | PRKDCLCKFYNALDH1A1KDM4E | |
| SCHEMBL3910992 | 0.82 | KDM4E (0.52) | PRKDCLCKFYNALDH1A1KDM4E | |
| SCHEMBL515642 | 0.81 | PRKDC (1.00) | PRKDCLCKFYNALDH1A1KDM4E | |
| SCHEMBL8574466 | 0.81 | KDM4E (0.50) | PRKDCLCKFYNALDH1A1KDM4E | |
| SCHEMBL4169467 | 0.80 | ALDH1A1 (0.59) | PRKDCLCKFYNALDH1A1KDM4E | |
| SCHEMBL6763991 | 0.80 | LCK (0.85) | LCKFYNALDH1A1KDM4EHPGD | |
| SCHEMBL1918763 | 0.80 | LCK (0.66) | LCKFYNALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024350-B1 | PIPERIDINE DERIVATIVES AS HUMAN PAPILLOMA VIRUS INHIBITORS | ANACONDA PHARMA (FR) | 2013-09-18 | — | — | EP | disclosed |
| EP-2024350-A1 | PIPERIDINE DERIVATIVES AS HUMAN PAPILLOMA VIRUS INHIBITORS | Anaconda Pharma (FR) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007135106-A1 | PIPERIDINE DERIVATIVES AS HUMAN PAPILLOMA VIRUS INHIBITORS | ANACONDA PHARMA (FR) | 2007-11-29 | — | — | WO | disclosed |