Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | ERN1 | O75460 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30575778 | 0.91 | PRKDC (0.82) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL698744 | 0.89 | PRKDC (0.81) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL30665931 | 0.89 | PRKDC (0.81) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL18270047 | 0.89 | PRKDC (0.81) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL2174504 | 0.89 | PRKDC (0.79) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL660822 | 0.88 | PRKDC (0.77) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL1620382 | 0.88 | LMNA (0.87) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL28786078 | 0.88 | PRKDC (0.77) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL14835649 | 0.88 | LMNA (0.87) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL28567780 | 0.86 | PRKDC (0.74) | PRKDCALDH1A1KDM4ETSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 454 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119198962-A | Method for detecting specific impurities in 2-bromo-4, 5-dimethoxy benzyl bromide | 扬州市普林斯医药科技有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-118459366-A | 2-Bromo-4, 5-dimethoxy benzaldehyde n-dodecylamine Schiff base and preparation method and application thereof | 连云港职业技术学院 | 2024-08-09 | — | — | CN | claimed |
| CN-118459365-A | 2-Bromo-4, 5-dimethoxy benzaldehyde derivative, and preparation method and application thereof | 连云港职业技术学院 | 2024-08-09 | — | — | CN | claimed |
| CN-117069732-B | Preparation method of benzo [ c ] phenanthridine natural product and derivative thereof | 沈阳药科大学 | 2024-04-26 | — | — | CN | claimed |
| CN-117069732-A | Preparation method of benzo [ c ] phenanthridine natural product and derivative thereof | 沈阳药科大学 | 2023-11-17 | — | — | CN | claimed |
| CN-114456184-B | 3-aryl isoquinoline derivative and preparation and application thereof | 南华大学附属第一医院 | 2023-08-22 | — | — | CN | claimed |
| CN-115463119-A | VEGFR-2 inhibitor and preparation and application thereof | 青岛科技大学 | 2022-12-13 | — | — | CN | claimed |
| CN-114716386-A | Novel exosome inhibitor and preparation method thereof | 北京和理咨询有限公司 | 2022-07-08 | — | — | CN | claimed |
| CN-114456184-A | 3-aryl isoquinoline derivative and preparation and application thereof | 南华大学附属第一医院 | 2022-05-10 | — | — | CN | claimed |
| CN-106749358-B | A method of synthesis 5- methoxyl group -4- hydroxyl -2- aldehyde radical phenyl boric acid pinacol ester | 雅本化学股份有限公司 | 2019-05-10 | — | — | CN | claimed |
| CN-102887904-A | 2,3-dioxyethyl-5-methyl-8,9-dimethoxy benzophenanthridine derivative, and preparation method and application thereof | UNIV GUANGXI NORMAL | 2013-01-23 | — | — | CN | claimed |
| CN-102018688-B | PTP1B inhibitor and synthesis and application thereof in preparation of medicine used for treating type II diabetes | INST OCEANOLOGY CHINESE ACAD | 2012-10-10 | — | — | CN | claimed |
| CN-101407474-B | Preparation of 2-bromo-4,5-dimethoxy benzenepropanenitrile | DONGHUA UNIVERSITY (CN) | 2011-12-14 | — | — | CN | claimed |
| CN-101412683-B | 2-bromo-4,5-dimethoxy cinnamonitrile and preparation thereof | DONGHUA UNIVERSITY (CN) | 2011-12-14 | — | — | CN | claimed |
| CN-100579947-C | Method for preparing di-(2,3-dibromo-4,5-dihydroxybenzyl)-ether | UNIV QINGDAO | 2010-01-13 | — | — | CN | claimed |
| CN-101412683-A | 2-bromo-4,5-dimethoxy cinnamonitrile and preparation thereof | UNIV DONGHUA (CN) | 2009-04-22 | — | — | CN | claimed |
| CN-101407474-A | Preparation of 2-bromo-4,5-dimethoxy benzenepropanenitrile | UNIV DONGHUA (CN) | 2009-04-15 | — | — | CN | claimed |
| US-20060084176-A1 | Detection of uronium salts | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-04-20 | — | — | US | claimed |
| US-4380629-A | Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime | MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) | 1983-04-19 | — | — | US | claimed |
| US-4147862-A | Method of preparing styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1979-04-03 | — | — | US | claimed |