Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 2/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341 | 0.89 | GABRA1 (0.44) | GABRA1LMNAGABRB2CA1CA2 | |
| Hydrochloric Acid SCHEMBL15609199 | 0.85 | GABRA1 (0.41) | GABRA1LMNAGABRB2CA1CA2 | |
| Phosphoric Acid SCHEMBL28178732 | 0.85 | GABRA1 (0.50) | PTPN5GABRA1LMNAGABRB2CA1 | |
| SCHEMBL8761362 | 0.82 | GABRA1 (0.50) | GABRA1LMNAGABRB2CA1CA2 | |
| Phosphoric Acid SCHEMBL28538604 | 0.79 | CA12 (0.46) | PTPN5GABRA1LMNAGABRB2CA1 | |
| Phosphoric Acid SCHEMBL28070787 | 0.78 | GABRA1 (0.54) | PTPN5GABRA1LMNAGABRB2CA1 | |
| SCHEMBL1841574 | 0.78 | GABRA1 (0.57) | PTPN5GABRA1LMNAGABRB2CA1 | |
| Phosphoric Acid SCHEMBL25430768 | 0.78 | CA12 (0.53) | PTPN5GABRA1LMNAGABRB2CA1 | |
| SCHEMBL28762441 | 0.78 | GABRA1 (0.57) | PTPN5GABRA1LMNAGABRB2CA1 | |
| Hydrogen Peroxide SCHEMBL9644435 | 0.76 | GABRA1 (0.56) | GABRA1LMNAGABRB2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553138-B1 | FLAME-RETARDANT POLYBUTYLENE TEREPHTHALATE RESIN COMPOSITION AND MOLDINGS | TORAY INDUSTRIES (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7135509-B2 | Suitable for machine component parts, electrical/electronic component parts, and automotive component parts, injection moldability, mechanical properties | TORAY INDUSTRIES, INC. (JP) | 2006-11-14 | — | — | US | disclosed |
| US-20060142438-A1 | Flame-retardant polybutylene terephthalate resin composition and formed article | TORAY INDUSTRIES, INC., A CORPORATION OF JAPAN (JP) | 2006-06-29 | — | — | US | disclosed |
| EP-1553138-A1 | FLAME-RETARDANT POLYBUTYLENE TEREPHTHALATE RESIN COMPOSITION AND MOLDINGS | TORAY INDUSTRIES, INC. (JP) | 2005-07-13 | — | — | EP | disclosed |