SCHEMBL3913009

SCHEMBL3913009

SC1Nc2ccccc2O1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.41
ALOX5 P09917 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
BRD4 O60885 1/20 0.38
CREBBP Q92793 1/20 0.38
IDO1 P14902 1/20 0.38
GAA P10253 4/20 0.36
KDM4E B2RXH2 2/20 0.36
NISCH Q9Y2I1 1/20 0.34
CYB5R3 P00387 1/20 0.34
NPSR1 Q6W5P4 1/20 0.31
HPGD P15428 2/20 0.31
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8651078 0.76 GAA (0.57) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL12984932 0.73 PARP1 (0.41) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL19442758 0.73 PARP1 (0.41) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL4286553 0.73 PARP1 (0.46) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL6097826 0.73 PARP1 (0.41) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL23722589 0.73 PARP1 (0.50) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL7063218 0.73 PARP1 (0.41) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL5830221 0.73 PARP1 (0.41) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL6097831 0.73 PARP1 (0.50) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL476800 0.73 PARP1 (0.41) PARP1ALOX5MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0814376-B1 Photographic couplers which release useful groups anchiomerically and their synthesis EASTMAN KODAK CO (US) 2001-10-24 EP claimed
EP-0929362-B1 COMPOSITIONS AND METHODS FOR ORE BENEFICIATION CYTEC TECH CORP (US) 2001-06-13 EP claimed
EP-0626379-B1 Process for the preparation of 2-chlorobenzothiazole or 2-chlorobenzoxazole BAYER AG (DE) 2001-03-21 EP claimed
EP-0499349-B1 Process for preparing a degradation resistant molded pulp horticultural container CHINET CO (US) 1997-07-09 EP claimed
EP-0626379-A2 Process for the preparation of 2-chlorobenzothiazole or 2-chlorobenzoxazole BAYER AG (DE) 1994-11-30 EP claimed
EP-0087701-B1 PROCESS FOR THE PREPARATION OF 2-CHLOROBENZOXAZOLS CASSELLA Aktiengesellschaft (DE) 1986-08-20 EP claimed
EP-0087701-A2 Process for the preparation of 2-chlorobenzoxazols CASSELLA Aktiengesellschaft (DE) 1983-09-07 EP claimed
EP-2024347-B1 PHENYLAMINO-BENZOXAZOLE SUBSTITUTED CARBOXYLIC ACIDS, METHOD FOR THEIR PRODUCTION AND USE THEREOF AS MEDICAMENTS SANOFI SA (FR) 2012-08-01 EP disclosed
EP-2024347-A1 PHENYLAMINO-BENZOXAZOLE SUBSTITUTED CARBOXYLIC ACIDS, METHOD FOR THEIR PRODUCTION AND USE THEREOF AS MEDICAMENTS sanofi-aventis (FR) 2009-02-18 EP disclosed
WO-2007131622-A1 PHENYLAMINO-BENZOXAZOLE SUBSTITUTED CARBOXYLIC ACIDS, METHOD FOR THEIR PRODUCTION AND USE THEREOF AS MEDICAMENTS SANOFI-AVENTIS (DE) 2007-11-22 WO disclosed
EP-1071674-B1 METHOD FOR PRODUCING CHLOROBENZOXAZOLENE BAYER CROPSCIENCE GMBH (DE) 2004-08-11 EP disclosed
EP-0626379-B1 Process for the preparation of 2-chlorobenzothiazole or 2-chlorobenzoxazole BAYER AG (DE) 2001-03-21 EP disclosed
EP-1071674-A1 METHOD FOR PRODUCING CHLOROBENZOXAZOLENE Aventis CropScience GmbH (DE) 2001-01-31 EP disclosed
US-5219904-A With organic peroxide NIPPON MEKTRON LIMITED (JP) 1993-06-15 US disclosed
US-5159026-A Containing halogen and peroxy compound NIPPON MEKTRON, LIMITED (JP) 1992-10-27 US disclosed
EP-0141053-B1 METHOD FOR THE PREPARATION OF 2-CHLORBENZOXAZOLES CASSELLA Aktiengesellschaft (DE) 1987-08-19 EP disclosed
EP-0087701-B1 PROCESS FOR THE PREPARATION OF 2-CHLOROBENZOXAZOLS CASSELLA Aktiengesellschaft (DE) 1986-08-20 EP disclosed
EP-0141053-A1 Method for the preparation of 2-chlorbenzoxazoles CASSELLA Aktiengesellschaft (DE) 1985-05-15 EP disclosed
EP-0087701-A2 Process for the preparation of 2-chlorobenzoxazols CASSELLA Aktiengesellschaft (DE) 1983-09-07 EP disclosed
EP-0044497-A2 Process for the production of heterocyclic substituted derivatives of 4-oxyphenoxy-alkane-carbonic acid HOECHST AKTIENGESELLSCHAFT (DE) 1982-01-27 EP disclosed