Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | CYB5R3 | P00387 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651078 | 0.76 | GAA (0.57) | PARP1ALOX5MEN1KMT2ALMNA | |
| SCHEMBL12984932 | 0.73 | PARP1 (0.41) | PARP1ALOX5MEN1KMT2ALMNA | |
| SCHEMBL3913009 | 0.73 | PARP1 (0.41) | PARP1ALOX5MEN1KMT2ALMNA | |
| SCHEMBL4286553 | 0.73 | PARP1 (0.46) | PARP1ALOX5MEN1KMT2ALMNA | |
| SCHEMBL7063218 | 0.73 | PARP1 (0.41) | PARP1ALOX5MEN1KMT2ALMNA | |
| SCHEMBL23722589 | 0.73 | PARP1 (0.50) | PARP1ALOX5MEN1KMT2ALMNA | |
| SCHEMBL6097831 | 0.73 | PARP1 (0.50) | PARP1ALOX5MEN1KMT2ALMNA | |
| SCHEMBL6097826 | 0.73 | PARP1 (0.41) | PARP1ALOX5MEN1KMT2ALMNA | |
| SCHEMBL5830221 | 0.73 | PARP1 (0.41) | PARP1ALOX5MEN1KMT2ALMNA | |
| SCHEMBL19442758 | 0.73 | PARP1 (0.41) | PARP1ALOX5MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071674-B1 | METHOD FOR PRODUCING CHLOROBENZOXAZOLENE | BAYER CROPSCIENCE GMBH (DE) | 2004-08-11 | — | — | EP | claimed |
| EP-0626379-B1 | Process for the preparation of 2-chlorobenzothiazole or 2-chlorobenzoxazole | BAYER AG (DE) | 2001-03-21 | — | — | EP | claimed |
| EP-1071674-A1 | METHOD FOR PRODUCING CHLOROBENZOXAZOLENE | Aventis CropScience GmbH (DE) | 2001-01-31 | — | — | EP | claimed |
| WO-1999031076-A1 | METHOD FOR PRODUCING CHLOROBENZOXAZOLENE | AVENTIS CROPSCIENCE GMBH (DE) | 1999-06-24 | — | — | WO | claimed |
| EP-0626379-A2 | Process for the preparation of 2-chlorobenzothiazole or 2-chlorobenzoxazole | BAYER AG (DE) | 1994-11-30 | — | — | EP | claimed |
| EP-0141053-B1 | METHOD FOR THE PREPARATION OF 2-CHLORBENZOXAZOLES | CASSELLA Aktiengesellschaft (DE) | 1987-08-19 | — | — | EP | claimed |
| EP-0087701-B1 | PROCESS FOR THE PREPARATION OF 2-CHLOROBENZOXAZOLS | CASSELLA Aktiengesellschaft (DE) | 1986-08-20 | — | — | EP | claimed |
| EP-0141053-A1 | Method for the preparation of 2-chlorbenzoxazoles | CASSELLA Aktiengesellschaft (DE) | 1985-05-15 | — | — | EP | claimed |
| EP-0087701-A2 | Process for the preparation of 2-chlorobenzoxazols | CASSELLA Aktiengesellschaft (DE) | 1983-09-07 | — | — | EP | claimed |
| US-20220168279-A1 | METHODS OF TREATING PAIN WITH A THIAZOLINE ANTI-HYPERALGESIC | ACADIA PHARM INC (US) | 2022-06-02 | — | — | US | disclosed |
| WO-2020159565-A1 | METHODS OF TREATING POST-SURGICAL PAIN WITH A THIAZOLINE ANTI-HYPERALGESIC AGENT | CERSCI THERAPEUTICS, INC. (US) | 2020-08-06 | — | — | WO | disclosed |
| EP-3252050-A1 | PHTHALAZINONES AND ISOQUINOLINONES AS ROCK INHIBITORS | Bristol-Myers Squibb Company (US) | 2017-12-06 | — | — | EP | disclosed |
| US-20130281476-A1 | Modulators of Muscarinic Receptors | VERTEX PHARMACEUTICALS INCORPORATED | 2013-10-24 | — | — | US | disclosed |
| US-8497295-B2 | Spiroindoline modulators of muscarinic receptors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-07-30 | — | — | US | disclosed |
| EP-0141053-A1 | Method for the preparation of 2-chlorbenzoxazoles | CASSELLA Aktiengesellschaft (DE) | 1985-05-15 | — | — | EP | disclosed |
| EP-0141053-A1 | Method for the preparation of 2-chlorbenzoxazoles | CASSELLA Aktiengesellschaft (DE) | 1985-05-15 | — | — | EP | disclosed |
| EP-0087701-A2 | Process for the preparation of 2-chlorobenzoxazols | CASSELLA Aktiengesellschaft (DE) | 1983-09-07 | — | — | EP | disclosed |
| EP-0087701-A2 | Process for the preparation of 2-chlorobenzoxazols | CASSELLA Aktiengesellschaft (DE) | 1983-09-07 | — | — | EP | disclosed |
| EP-0087701-A2 | Process for the preparation of 2-chlorobenzoxazols | CASSELLA Aktiengesellschaft (DE) | 1983-09-07 | — | — | EP | disclosed |
| EP-0066248-A1 | Process for the preparation of halogeno-2-mercaptobenzoxazoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-12-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281476-A1 | Modulators of Muscarinic Receptors | CHRM3, CHRM5, CHRM2 | PARP1 4245/4885ALOX5 1105/4885MEN1 2672/4885 |
| US-20220168279-A1 | METHODS OF TREATING PAIN WITH A THIAZOLINE ANTI-HYPERALGESIC | OPRK1, OPRL1, OPRD1 | PARP1 3595/4885ALOX5 267/4885MEN1 2726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.