SCHEMBL7063218

SCHEMBL7063218

[NH]C1Nc2ccccc2O1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.41
ALOX5 P09917 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
BRD4 O60885 1/20 0.38
CREBBP Q92793 1/20 0.38
GAA P10253 4/20 0.36
KDM4E B2RXH2 2/20 0.36
NISCH Q9Y2I1 1/20 0.34
CYB5R3 P00387 1/20 0.34
NPSR1 Q6W5P4 1/20 0.31
HPGD P15428 2/20 0.31
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8651078 0.76 GAA (0.57) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL3913009 0.73 PARP1 (0.41) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL19442758 0.73 PARP1 (0.41) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL4286553 0.73 PARP1 (0.46) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL6097831 0.73 PARP1 (0.50) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL23722589 0.73 PARP1 (0.50) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL12984932 0.73 PARP1 (0.41) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL5830221 0.73 PARP1 (0.41) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL6097826 0.73 PARP1 (0.41) PARP1ALOX5MEN1KMT2ALMNA
SCHEMBL476800 0.73 PARP1 (0.41) PARP1ALOX5MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6620580-B2 Photographic element comprising a support bearing a blue light sensitive record containing at least three layers having different levels of light sensitivity arranged in the order slowest to fastest with the slowest layer closest to the EASTMAN KODAK COMPANY 2003-09-16 US disclosed
US-20030143498-A1 Color negative element containing triple-coated blue record and method of imaging using same EASTMAN KODAK COMPANY 2003-07-31 US disclosed
EP-1004932-B1 Photographic and imaging elements including biaxially oriented polyolefin sheets EASTMAN KODAK CO (US) 2003-06-04 EP disclosed
EP-1312978-A1 Color negative element containing triple-coated blue record and method of imaging using same EASTMAN KODAK COMPANY (US) 2003-05-21 EP disclosed
EP-1004932-A1 Photographic and imaging elements including biaxially oriented polyolefin sheets EASTMAN KODAK COMPANY (US) 2000-05-31 EP disclosed
US-6030742-A CURL RESISTANCE; A PHOTOSENSITIVE SILVER HALIDE LAYER COMPRISING AT LEAST ONE DYE FORMING COUPLER, A SUPPORT COMPRISING PAPER HAVING LAMINATED A TOP AND BOTTOM SHEET OF BIAXIALLY ORIENTED POLYETHYLENE EASTMAN KODAK COMPANY (US) 2000-02-29 US disclosed
EP-0596575-B1 Photographic material and process comprising a pyrazolotriazole moiety EASTMAN KODAK CO (US) 1999-01-27 EP disclosed
US-5719292-A REACTING IN PRESENCE OF BASE COUPLER COMPOUND HAVING HYDROGEN AT COUPLING SITE AND MIXED DISULFIDE COMPRISING TETRAZOLE OR OXADIAZOLE LINKED TO ONE SULFUR ATOM AND ALKYL OR ARYL GROUP LINKED TO OTHER EASTMAN KODAK COMPANY (US) 1998-02-17 US disclosed
US-5641613-A SUPPORT BEARING LIGHT SENSITIVE SILVER HALIDE LAYER CONTAINING BICYCLIC AZOLE COUPLER, AZOPYRAZOLONE MASKING COUPLER, LOW IMPACT DEVELOPMENT INHIBITOR RELEASING COUPLER EASTMAN KODAK COMPANY (US) 1997-06-24 US disclosed
EP-0646842-A1 Photographic element containing an azopyrazolone masking coupler exhibiting improved keeping EASTMAN KODAK COMPANY (US) 1995-04-05 EP disclosed
EP-0596575-A1 Photographic material and process comprising a pyrazolotriazole moiety EASTMAN KODAK COMPANY (US) 1994-05-11 EP disclosed
US-5306607-A Releases development inhibitor upon oxidative coupling EASTMAN KODAK COMPANY (US) 1994-04-26 US disclosed
US-4857447-A Silver halide color photographic light-sensitive material containing a coupler having a dye moiety FUJI PHOTO FILM CO., LTD. (JP) 1989-08-15 US disclosed