Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.42 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.42 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.42 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.42 |
| ▸ | CBFB | Q13951 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645353 | 0.87 | ALDH1A1 (0.46) | HSD17B10NAPRTALDH1A1CYP1A2HTT | |
| SCHEMBL15421259 | 0.81 | ALDH1A1 (0.42) | HSD17B10ALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL4066831 | 0.78 | HSD17B10 (0.52) | HSD17B10NAPRTALDH1A1CYP1A2HTT | |
| SCHEMBL28100309 | 0.78 | ALDH1A1 (0.55) | HSD17B10NAPRTALDH1A1CYP1A2HTT | |
| SCHEMBL7406905 | 0.78 | ALDH1A1 (0.52) | HSD17B10NAPRTALDH1A1CYP1A2HTT | |
| SCHEMBL7841883 | 0.78 | ALDH1A1 (0.47) | HSD17B10NAPRTALDH1A1CYP1A2HTT | |
| SCHEMBL2459851 | 0.76 | ALDH1A1 (0.47) | HSD17B10NAPRTALDH1A1CYP1A2HTT | |
| SCHEMBL9900080 | 0.76 | ALDH1A1 (0.46) | HSD17B10NAPRTALDH1A1CYP1A2HTT | |
| SCHEMBL7769606 | 0.76 | ALDH1A1 (0.49) | ALDH1A1HTTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL1743263 | 0.74 | SMN1; SMN2 (0.46) | HSD17B10ALDH1A1CYP1A2SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506261-B1 | TRISAZO DYES FOR INK JET PRINTING | FUJIFILM IMAGING COLORANTS LTD (GB) | 2009-11-18 | — | — | EP | claimed |
| US-7481522-B2 | Compositions and inks containing disazo dyes | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2009-01-27 | — | — | US | claimed |
| EP-1633716-A4 | BIARYLMETHYL INDOLINES, INDOLES AND TETRAHYDROQUINOLINES, USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-03-26 | — | — | EP | claimed |
| US-7129264-B2 | Biarylmethyl indolines and indoles as antithromboembolic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-10-31 | — | — | US | claimed |
| US-7052538-B2 | Trisazo dyes for ink jet printing | AVECIA LIMITED (GB) | 2006-05-30 | — | — | US | claimed |
| EP-1633716-A2 | BIARYLMETHYL INDOLINES, INDOLES AND TETRAHYDROQUINOLINES, USEFUL AS SERINE PROTEASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2006-03-15 | — | — | EP | claimed |
| US-20050217535-A1 | Trisazo dyes for ink jet printing | AVECIA INKJET LIMITED (GB) | 2005-10-06 | — | — | US | claimed |
| EP-1506261-A1 | TRISAZO DYES FOR INK JET PRINTING | Avecia Limited (GB) | 2005-02-16 | — | — | EP | claimed |
| WO-2004094372-A2 | COMPOUNDS USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-11-04 | — | — | WO | claimed |
| US-20040220206-A1 | Biarylmethyl indolines, indoles and tetrahydroquinolines, useful as serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-11-04 | — | — | US | claimed |
| WO-2003095562-A1 | TRISAZO DYES FOR INK JET PRINTING | AVECIA LIMITED (GB) | 2003-11-20 | — | — | WO | claimed |
| EP-1521808-B1 | COMPOSITIONS AND INKS CONTAINING DISAZO DYES | FUJIFILM IMAGING COLORANTS LTD (GB) | 2012-08-01 | — | — | EP | disclosed |
| EP-1506261-B1 | TRISAZO DYES FOR INK JET PRINTING | FUJIFILM IMAGING COLORANTS LTD (GB) | 2009-11-18 | — | — | EP | disclosed |
| US-7481522-B2 | Compositions and inks containing disazo dyes | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2009-01-27 | — | — | US | disclosed |
| EP-1633716-A4 | BIARYLMETHYL INDOLINES, INDOLES AND TETRAHYDROQUINOLINES, USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-03-26 | — | — | EP | disclosed |
| WO-2003095562-A1 | TRISAZO DYES FOR INK JET PRINTING | AVECIA LIMITED (GB) | 2003-11-20 | — | — | WO | disclosed |
| US-6222023-B1 | USEFUL AS REACTIVE DYES; DYEING PERFORMANCE SUCH AS UILD-UP PROPERTY, LEVELING PROPERTY; COLORFASTNESS OF DYED PRODUCT, REPRODUCIBILITY; FOR DYEING FIBERS DARK BLUE; SUITED FOR CELLULOSE FIBERS | SUMITOMO CHEMICAL, COMPANY, LIMITED (JP) | 2001-04-24 | — | — | US | disclosed |
| US-6214977-B1 | DARK-BLUE DYEING OF CELLULOSE FIBER MATERIALS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-04-10 | — | — | US | disclosed |
| US-5998591-A | COLORFASTNESS; PHOTOSTABILITY; RED, ORANGE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-12-07 | — | — | US | disclosed |
| US-5962655-A | RED DYE FOR CELLULOSE, POLYAMIDES, POLYURETHANES, LEATHER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220206-A1 | Biarylmethyl indolines, indoles and tetrahydroquinolines, useful as serine protease inhibitors | TFPI, TFPI2, F2 | HSD17B10 2048/4885NAPRT 4398/4885ALDH1A1 2594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.