Lisofylline

Lisofylline

SCHEMBL39131

C[C@@H](O)CCCCn1c(=O)c2c(ncn2C)n(C)c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 7/20 0.67
TNF P01375 4/20 0.67
USP2 O75604 1/20 0.67
LMNA P02545 1/20 0.67
CYP1A2 P05177 1/20 0.67
TSHR P16473 1/20 0.67
NFKB1 P19838 1/20 0.67
ACHE P22303 1/20 0.67
PDE4A P27815 1/20 0.67
PMP22 Q01453 1/20 0.67
PDE4B Q07343 1/20 0.67
PDE4C Q08493 1/20 0.67
PDE4D Q08499 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
RXFP1 Q9HBX9 1/20 0.67
CHIT1 Q13231 1/20 0.58
CHIA Q9BZP6 1/20 0.58
AKR1B1 P15121 1/20 0.56
GLA P06280 1/20 0.55
BLM P54132 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lisofylline SCHEMBL680306 1.00 ADORA2B (0.67) ADORA2BTNFUSP2LMNACYP1A2
Lisofylline, (S)- SCHEMBL1495100 1.00 ADORA2B (0.67) ADORA2BTNFUSP2LMNACYP1A2
SCHEMBL6778207 0.99 ADORA2B (0.66) ADORA2BTNFUSP2LMNACYP1A2
SCHEMBL6778919 0.99 ADORA2B (0.66) ADORA2BTNFUSP2LMNACYP1A2
SCHEMBL6777369 0.99 ADORA2B (0.66) ADORA2BTNFUSP2LMNACYP1A2
SCHEMBL8699282 0.99 ADORA2B (0.66) ADORA2BTNFUSP2LMNACYP1A2
SCHEMBL6783783 0.99 ADORA2B (0.66) ADORA2BTNFUSP2LMNACYP1A2
SCHEMBL8700060 0.99 ADORA2B (0.66) ADORA2BTNFUSP2LMNACYP1A2
SCHEMBL6774460 0.99 ADORA2B (0.66) ADORA2BTNFUSP2LMNACYP1A2
Lisofylline SCHEMBL10517408 0.99 ADORA2B (0.66) ADORA2BTNFUSP2LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6758 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4736261-A1 BATTERY PACK Avant Tecno Oy (FI) 2026-05-06 EP claimed
US-20250177565-A1 METHODS AND MATERIALS FOR INHIBITING/PREVENTING THE TRAFFICKING OF MONOCYTES TO THE CENTRAL NERVOUS SYSTEM DARTMOUTH COLLEGE (US) 2025-06-05 US claimed
CN-116787024-B Copper-plating-free gas shielded welding wire surface coating 苏州骐骥焊接材料有限公司 2025-05-06 CN claimed
US-20250140876-A1 SOLID OXIDE CELL AND MANUFACTURING METHOD THEREOF SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2025-05-01 US claimed
US-12280057-B2 Vasoactive topical compound to affect tissue blood flow, reduce tissue necrosis and promote healing SOUTH DAKOTA BOARD OF REGENTS (US) 2025-04-22 US claimed
US-20250123282-A1 METHODS FOR EVALUATION AND TREATMENT OF TYROSINE KINASE INHIBITOR (TKI)-RESISTANT ACUTE MYELOID LEUKEMIA UNIV LOMA LINDA (US) 2025-04-17 US claimed
CN-119768941-A Metal-solid oxide composite, method for preparing the same, and solid oxide battery including the same 三星电机株式会社 2025-04-04 CN claimed
WO-2025064666-A1 MACHINE LEARNING METHODS AND SYSTEMS FOR ACUTE RESPIRATORY DISTRESS SYNDROME PATIENT SUB-PHENOTYPING GEN1E LIFESCIENCES INC. (US) 2025-03-27 WO claimed
CN-119698702-A Solid oxide cell and method for manufacturing same 三星电机株式会社 2025-03-25 CN claimed
CN-119698703-A Porous solid oxide composite and solid oxide cell including the same 三星电机株式会社 2025-03-25 CN claimed
WO-1983003975-A1 ANTIBACTERIAL PROTECTIVE CAP FOR CONNECTORS BAXTER TRAVENOL LABORATORIES, INC. (US) 1983-11-24 WO claimed
WO-1983003837-A1 INACTIVATED POLYURETHANE AND METHOD FOR PREPARING IT PROTECTOR AGENTUR AB (SE) 1983-11-10 WO claimed
EP-0082856-A1 CONTAINER FOR SAMPLE TESTING. BECKMAN INSTRUMENTS INC (US) 1983-07-06 EP claimed
WO-1983002200-A1 METHOD FOR MANUFACTURING SEMI-CONDUCTING DEVICES AND SEMI-CONDUCTING DEVICES THUS OBTAINED FRISSON, LOUIS 1983-06-23 WO claimed
WO-1983000102-A1 CONTAINER FOR SAMPLE TESTING BECKMAN INSTRUMENTS INC (US) 1983-01-20 WO claimed
EP-0020687-A1 CLOSED DISPOSABLE CONTAINER. APPLIC GAZ SA (FR) 1981-01-07 EP claimed
WO-1980002390-A1 METHOD OF PAINTING CATERPILLAR TRACTOR CO 1980-11-13 WO claimed
EP-0018833-A2 Compounded perfumery composition BUSH BOAKE ALLEN Limited (GB) 1980-11-12 EP claimed
WO-1980001312-A1 CLOSED METAL CONTAINER AND MANUFACTURING PROCESS THEREOF APPLIC DES GAZ SOC (FR) 1980-06-26 WO claimed
US-4042975-A Means for protecting batters from hand injuries NEW PRODUCTS DEVELOPMENT, INC. (US) 1977-08-23 US claimed