Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2062827 | 1.00 | KEAP1 (0.57) | KEAP1NFE2L2KCNN4CHRM3ALDH1A1 | |
| SCHEMBL2763726 | 0.98 | KEAP1 (0.56) | KEAP1NFE2L2KCNN4CHRM3ALDH1A1 | |
| SCHEMBL5262791 | 0.87 | KEAP1 (0.50) | KEAP1NFE2L2KCNN4CHRM3ALDH1A1 | |
| SCHEMBL5668052 | 0.82 | CHRM2 (0.50) | KEAP1NFE2L2KCNN4CHRM3ALDH1A1 | |
| SCHEMBL3912116 | 0.82 | CHRM2 (0.50) | KEAP1NFE2L2KCNN4CHRM3ALDH1A1 | |
| SCHEMBL24133064 | 0.80 | KEAP1 (0.54) | KEAP1NFE2L2CHRM3ALDH1A1CHRM2 | |
| SCHEMBL1471859 | 0.80 | KCNN4 (0.51) | KEAP1NFE2L2KCNN4CHRM3ALDH1A1 | |
| SCHEMBL10334645 | 0.79 | CHRM2 (0.47) | KEAP1NFE2L2KCNN4CHRM3ALDH1A1 | |
| SCHEMBL10335659 | 0.78 | CA1 (0.43) | ALDH1A1CES1 | |
| SCHEMBL10335594 | 0.78 | MEN1 (0.41) | SLC6A3CYP1A2POLBCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544708-B2 | Azabicyclo derivatives as muscarinic receptor antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2009-06-09 | — | — | US | disclosed |
| US-20060111425-A1 | Azabicyclo derivatives as muscarinic receptor antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111425-A1 | Azabicyclo derivatives as muscarinic receptor antagonists | CHRM3, CHRM5, CHRM2 | KEAP1 2017/4885NFE2L2 4262/4885KCNN4 1440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.