Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3913639 | 0.87 | KEAP1 (0.57) | KEAP1NFE2L2KCNN4CHRM3ALDH1A1 | |
| SCHEMBL2062827 | 0.87 | KEAP1 (0.57) | KEAP1NFE2L2KCNN4CHRM3ALDH1A1 | |
| SCHEMBL2763726 | 0.85 | KEAP1 (0.56) | KEAP1NFE2L2KCNN4CHRM3ALDH1A1 | |
| SCHEMBL6453670 | 0.83 | POLB (0.44) | KEAP1NFE2L2CHRM3ALDH1A1CHRM2 | |
| SCHEMBL28802479 | 0.81 | KEAP1 (0.44) | KEAP1NFE2L2MAPTKMT2ACHRM3 | |
| SCHEMBL5668052 | 0.79 | CHRM2 (0.50) | KEAP1NFE2L2MAPTKMT2AKCNN4 | |
| SCHEMBL3912116 | 0.79 | CHRM2 (0.50) | KEAP1NFE2L2MAPTKMT2AKCNN4 | |
| SCHEMBL1471859 | 0.77 | KCNN4 (0.51) | KEAP1NFE2L2KCNN4CHRM3ALDH1A1 | |
| SCHEMBL26134188 | 0.77 | CHRM3 (0.55) | KEAP1NFE2L2MAPTKMT2ACHRM3 | |
| SCHEMBL29116795 | 0.76 | KEAP1 (0.56) | KEAP1NFE2L2MAPTKMT2ACHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796667-A2 | MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035282-A2 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-04-06 | — | — | WO | disclosed |