SCHEMBL391371

SCHEMBL391371

CCOC(=O)C(Cl)=NO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL391370 1.00
SCHEMBL405356 1.00
SCHEMBL28265341 0.98 ALDH1A1 (0.40)
SCHEMBL12406763 0.81
SCHEMBL9735271 0.81
SCHEMBL22840045 0.79
SCHEMBL13901633 0.79 MAPT (0.48)
SCHEMBL20204382 0.77 ALDH1A1 (0.39)
SCHEMBL16683481 0.77 ALDH1A1 (0.39)
SCHEMBL16739278 0.77 ALDH1A1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 573 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116497528-A Flexible conductive fiber film based on oxime urethane bond, preparation method and application 陕西科技大学 2023-07-28 CN claimed
CN-105682461-B Pesticidal combination and relative method 美国陶氏益农公司 2019-06-14 CN claimed
US-9497966-B2 Pesticidal compositions and related methods DOW AGROSCIENCES LLC (US) 2016-11-22 US claimed
EP-3060047-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS Dow AgroSciences, LLC (US) 2016-08-31 EP claimed
WO-2015061157-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2015-04-30 WO claimed
US-20150111732-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC 2015-04-23 US claimed
US-8367847-B2 Production of monatin enantiomers CARGILL, INCORPORATED (US) 2013-02-05 US claimed
EP-2536714-A2 A NOVEL 5-MEMBERED HETEROCYCLE DERIVATIVES AND MANUFACTURING PROCESS THEREOF Il-Dong Pharm. Co., Ltd. (KR) 2012-12-26 EP claimed
WO-2011102660-A2 A NOVEL 5-MEMBERED HETEROCYCLE DERIVATIVES AND MANUFACTURING PROCESS THEREOF ILDONG PHARM CO., LTD. (KR) 2011-08-25 WO claimed
CN-102105466-A Isoxazole derivatives and their use as metabotropic glutamate receptor potentiators ASTRAZENECA AB 2011-06-22 CN claimed
US-20100022545-A1 Metabotropic Glutamate Receptor Isoxazole Ligands and Their Use as Potentiators - 286 CACCIOLA JOSEPH 2010-01-28 US claimed
WO-2009148403-A1 ISOXAZOLE DERIVATIVES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS ASTRAZENECA AB (SE) 2009-12-10 WO claimed
US-20090306158-A1 Metabotropic Glutamate Receptor Isoxazole Ligands and Their Use as Potentiators 286 ASTRAZENECA AB (SE) 2009-12-10 US claimed
EP-2125830-A1 NEW PROCESS FOR PREPARING 3-METHYL-4-PHENYLISOXAZOLOÝ3,4-D¨PYRIDAZIN-7(6H)-ONE Almirall, S.A. (ES) 2009-12-02 EP claimed
WO-2009044245-A2 PRODUCTION OF MONATIN ENANTIOMERS CARGILL, INCORPORATED (US) 2009-04-09 WO claimed
US-20090088577-A1 PRODUCTION OF MONATIN ENANTIOMERS CARGILL, INCORPORATED 2009-04-02 US claimed
WO-2008107064-A1 NEW PROCESS FOR PREPARING 3-METHYL-4-PHENYLISOXAZOLO[3,4-D]PYRIDAZIN-7(6H)-ONE ALMIRALL S.A. (ES) 2008-09-12 WO claimed
EP-0438314-B1 Process for the production of 3-(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl) indole TECHNOLOGY FINANCE CORP (ZA) 1994-04-27 EP claimed
US-5128482-A Process for the production of 3-1(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl) indole TECHNOLOGY FINANCE CORPORATION (PROPRIETARY) LIMITED (ZA) 1992-07-07 US claimed
EP-0438314-A1 Process for the production of 3-(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl) indole TECHNOLOGY FINANCE CORPORATION (PROPRIETARY) LIMITED (ZA) 1991-07-24 EP claimed