SCHEMBL405356

SCHEMBL405356

CCOC(=O)/C(Cl)=N/O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL391371 1.00
SCHEMBL391370 1.00
SCHEMBL28265341 0.98 ALDH1A1 (0.40)
SCHEMBL12406763 0.81
SCHEMBL9735271 0.81
SCHEMBL22840045 0.79
SCHEMBL13901633 0.79 MAPT (0.48)
SCHEMBL20204382 0.77 ALDH1A1 (0.39)
SCHEMBL16683481 0.77 ALDH1A1 (0.39)
SCHEMBL16739278 0.77 ALDH1A1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 499 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113463398-A Preparation method of black hole external composite functional powder and textile after-finishing liquid 聚治(苏州)纳米科技有限公司 2021-10-01 CN claimed
US-20210157242-A1 PHOTORESIST-REMOVING LIQUID AND PHOTORESIST-REMOVING METHOD HUAYING RESEARCH CO., LTD (CN) 2021-05-27 US claimed
EP-3663857-A1 PHOTORESIST STRIPPING SOLUTION AND METHOD OF STRIPPING PHOTORESIST Huaying Research Co., Ltd (CN) 2020-06-10 EP claimed
US-12630554-B2 Pyrimidinone compounds and uses thereof HUTCHISON MEDIPHARMA LIMITED (CN) 2026-05-19 US disclosed
EP-4178620-B1 PLASMA KALLIKREIN INHIBITORS MERCK SHARP & DOHME LLC (US) 2026-04-01 EP disclosed
EP-4380921-B1 D3 DOPAMINE RECEPTOR-SELECTIVE NEGATIVE ALLOSTERIC MODULATORS US HEALTH (US) 2026-01-28 EP disclosed
US-12528786-B2 Plasma kallikrein inhibitors MERCK SHARP & DOHME LLC (US) 2026-01-20 US disclosed
EP-4635494-A2 AMIDO HETEROAROMATIC COMPOUNDS Astrazeneca AB (SE) 2025-10-22 EP disclosed
EP-4514782-B1 AMIDO HETEROAROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF LIVER DISEASES ASTRAZENECA AB (SE) 2025-09-10 EP disclosed
US-12391690-B2 Compounds as autotaxin inhibitors and pharmaceutical compositions comprising the same LIGACHEM BIOSCIENCES INC. (KR) 2025-08-19 US disclosed
EP-3980400-B1 PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS UNIV EMORY (US) 2025-08-06 EP disclosed
EP-0609798-A1 4-Benzoyl isoxazoles and their use as herbicides RHONE POULENC AGRICULTURE LTD. (GB) 1994-08-10 EP disclosed
US-5328907-A Treatment of allograft rejection in mammals and antiinflammatory agents SYNTEX (U.S.A.) INC. (US) 1994-07-12 US disclosed
US-5284853-A Hypotensive agents AMERICAN CYANAMID COMPANY (US) 1994-02-08 US disclosed
US-5273989-A 3,5-disubstituted 2-isoxazolines and isoxazoles, agents containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-12-28 US disclosed
US-5258397-A FOR TREATMENT OF EPILEPSY; SIDE EFFECT REDUCTION NOVAPHARME (FR) 1993-11-02 US disclosed
US-5108999-A For treating inflammation, autoimmune disease or allograft rejection in mammals SYNTEX (U.S.A.) INC. (US) 1992-04-28 US disclosed
WO-1992003050-A1 FUNGICIDAL SULFONEOXIME ESTERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-03-05 WO disclosed
EP-0440503-A1 4-Isoxazolecarboxamide derivatives SYNTEX (U.S.A.) INC. (US) 1991-08-07 EP disclosed
US-5001124-A 4-isoxazolecarboxamide derivatives SYNTEX (U.S.A.) INC. (US) 1991-03-19 US disclosed