Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 8/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 4/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 4/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915572 | 1.00 | HTR3A (0.35) | HTR3ACHRM3CHRM2CHRM1ALDH1A1 | |
| SCHEMBL1922997 | 1.00 | HTR3A (0.35) | HTR3ACHRM3CHRM2CHRM1ALDH1A1 | |
| SCHEMBL2104670 | 0.84 | CHRM3 (0.35) | HTR3ACHRM3CHRM2CHRM1 | |
| SCHEMBL18686611 | 0.82 | CHRM3 (0.47) | HTR3ACHRM3CHRM2CHRM1TDP1 | |
| SCHEMBL6223543 | 0.82 | CHRM3 (0.47) | HTR3ACHRM3CHRM2CHRM1TDP1 | |
| SCHEMBL7329746 | 0.82 | CHRM3 (0.47) | HTR3ACHRM3CHRM2CHRM1TDP1 | |
| Hydrochloric Acid SCHEMBL3744342 | 0.81 | CHRM3 (0.46) | HTR3ACHRM3CHRM2CHRM1TDP1 | |
| Hydrochloric Acid SCHEMBL18980736 | 0.81 | CHRM3 (0.46) | HTR3ACHRM3CHRM2CHRM1TDP1 | |
| SCHEMBL4173981 | 0.79 | CHRM3 (0.42) | CHRM3CHRM2CHRM1ALDH1A1POLB | |
| SCHEMBL4173985 | 0.79 | CHRM3 (0.42) | CHRM3CHRM2CHRM1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579345-B2 | Muscarinic acetylcholine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2009-08-25 | — | — | US | disclosed |
| US-20070232599-A1 | Muscarinic Acetylcholine Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232599-A1 | Muscarinic Acetylcholine Receptor Antagonists | CHRM3, CHRNG, CHRM2 | HTR3A 152/4885CHRM3 1/4885CHRM2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.