Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | HTR3A | P46098 | 13/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3913737 | 0.84 | HTR3A (0.35) | CHRM3HTR3ACHRM2CHRM1 | |
| SCHEMBL1922997 | 0.84 | HTR3A (0.35) | CHRM3HTR3ACHRM2CHRM1 | |
| SCHEMBL3915572 | 0.84 | HTR3A (0.35) | CHRM3HTR3ACHRM2CHRM1 | |
| SCHEMBL1923238 | 0.77 | LMNA (0.36) | HTR3A | |
| SCHEMBL13714935 | 0.77 | LMNA (0.36) | HTR3A | |
| SCHEMBL1698594 | 0.74 | — | — | |
| SCHEMBL14232024 | 0.71 | — | — | |
| SCHEMBL15030963 | 0.71 | — | — | |
| SCHEMBL3546248 | 0.68 | LMNA (0.32) | — | |
| SCHEMBL7293969 | 0.68 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163740-B2 | 6-substituted benzoxazines | HOFFMANN-LA ROCHE INC. (US) | 2012-04-24 | — | — | US | disclosed |
| US-20100063037-A1 | 6-SUBSTITUTED BENZOXAZINES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063037-A1 | 6-SUBSTITUTED BENZOXAZINES | HTR5A, NPY5R, GABRA5 | CHRM3 674/4885HTR3A 30/4885CHRM2 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.