Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 6/20 | 0.35 |
| ▸ | RORC | P51449 | 5/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907521 | 0.93 | REN (0.36) | RENRORCPIK3CDPIK3CAGRM5 | |
| SCHEMBL3905412 | 0.93 | REN (0.37) | RENRORCPIK3CDPIK3CAGRM5 | |
| SCHEMBL3906174 | 0.93 | REN (0.39) | RENRORCPIK3CDPIK3CAGRM5 | |
| SCHEMBL3907991 | 0.92 | REN (0.36) | RENRORCPIK3CDPIK3CAGRM5 | |
| SCHEMBL3908632 | 0.91 | UTS2R (0.38) | RENPIK3CDPIK3CAGRM5 | |
| SCHEMBL4145730 | 0.91 | REN (0.38) | RENRORCPIK3CDPIK3CAGRM5 | |
| SCHEMBL3915187 | 0.90 | REN (0.43) | RENRORC | |
| SCHEMBL8236339 | 0.90 | REN (0.43) | RENRORC | |
| SCHEMBL3915790 | 0.90 | REN (0.37) | RENRORCPIK3CDPIK3CAGRM5 | |
| SCHEMBL3908330 | 0.90 | REN (0.39) | RENPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029981-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES | NOVARTIS AG (CH) | 2009-01-29 | — | — | US | disclosed |
| EP-2018862-A1 | Substituted piperidines as therapeutic compounds | Speedel Experimenta AG (CH) | 2009-01-28 | — | — | EP | disclosed |
| EP-1973903-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES | Speedel Experimenta AG (CH) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007082907-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES | SPEEDEL EXPERIMENTA AG (CH) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029981-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES | REN, AGTR2, ACE | REN 1/4885RORC 3676/4885PIK3CD 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.