Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.71 |
| ▸ | BACE1 | P56817 | 9/20 | 0.59 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5435440 | 1.00 | BCHE (0.71) | BCHEBACE1APAF1SLC6A11 | |
| SCHEMBL3903568 | 1.00 | BCHE (0.71) | BCHEBACE1APAF1SLC6A11 | |
| SCHEMBL5444846 | 1.00 | BCHE (0.71) | BCHEBACE1APAF1SLC6A11 | |
| SCHEMBL3905025 | 1.00 | BCHE (0.71) | BCHEBACE1APAF1SLC6A11 | |
| SCHEMBL5444850 | 1.00 | BCHE (0.71) | BCHEBACE1APAF1SLC6A11 | |
| SCHEMBL5435433 | 1.00 | BCHE (0.71) | BCHEBACE1APAF1SLC6A11 | |
| SCHEMBL3905032 | 1.00 | BCHE (0.71) | BCHEBACE1APAF1SLC6A11 | |
| SCHEMBL14637748 | 0.87 | BCHE (0.53) | BCHEBACE1SLC6A11 | |
| SCHEMBL14636685 | 0.87 | BCHE (0.53) | BCHEBACE1SLC6A11 | |
| SCHEMBL3491209 | 0.86 | BCHE (0.64) | BCHEBACE1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498436-B2 | Substituted hydroxyethylamines | PHARMACIA & UPJOHN COMPANY LLC (US) | 2009-03-03 | — | — | US | disclosed |
| US-20060106256-A1 | Substituted hydroxyethylamines | PHARMACIA & UPJOHN COMPANY | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106256-A1 | Substituted hydroxyethylamines | HNMT, PNMT, BCHE | BCHE 3/4885BACE1 26/4885APAF1 3273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.