SCHEMBL3915865

SCHEMBL3915865

CO[SiH](OC)C(C)OC(=O)c1ccccn1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.52
KDM4E B2RXH2 4/20 0.48
MAPT P10636 2/20 0.48
POLB P06746 1/20 0.48
ALDH1A1 P00352 2/20 0.47
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
PKM P14618 4/20 0.45
LMNA P02545 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
P4HTM Q9NXG6 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HTT P42858 1/20 0.44
GSK3B P49841 1/20 0.44
SMN1; SMN2 Q16637 4/20 0.42
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
MEN1 O00255 1/20 0.42
ALPL P05186 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3912030 0.84 KMT2A (0.49) KMT2AKDM4EMAPTPOLBALDH1A1
SCHEMBL3912349 0.82 KMT2A (0.45) KMT2AKDM4EMAPTPOLBALDH1A1
SCHEMBL30731163 0.82 KMT2A (0.58) KMT2AKDM4EMAPTPOLBALDH1A1
SCHEMBL9944382 0.82 KMT2A (0.58) KMT2AKDM4EMAPTPOLBALDH1A1
SCHEMBL3919092 0.80 KMT2A (0.43) KMT2AKDM4EMAPTPOLBALDH1A1
SCHEMBL14354348 0.80 KMT2A (0.57) KMT2AKDM4EMAPTPOLBALDH1A1
Hydrochloric Acid SCHEMBL30779160 0.80 KMT2A (0.57) KMT2AKDM4EMAPTPOLBALDH1A1
Hydrochloric Acid SCHEMBL29121031 0.80 KMT2A (0.57) KMT2AKDM4EMAPTPOLBALDH1A1
SCHEMBL3912354 0.80 PKM (0.50) KMT2AKDM4EMAPTPOLBALDH1A1
SCHEMBL27958638 0.79 KMT2A (0.56) KMT2AKDM4EMAPTPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 EP disclosed