SCHEMBL3912349

SCHEMBL3912349

CCC(OC(=O)c1ccccn1)[SiH](OC)OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.45
PKM P14618 4/20 0.44
KDM4E B2RXH2 3/20 0.44
MAPT P10636 2/20 0.44
POLB P06746 1/20 0.44
NPC1 O15118 4/20 0.43
RAB9A P51151 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
MITF O75030 1/20 0.43
ALDH1A1 P00352 5/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
PAX8 Q06710 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.40
LMNA P02545 1/20 0.40
NAPRT Q6XQN6 1/20 0.40
P4HTM Q9NXG6 1/20 0.40
APP P05067 1/20 0.40
MEN1 O00255 1/20 0.40
GSK3B P49841 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3919092 0.89 KMT2A (0.43) KMT2APKMKDM4EMAPTPOLB
SCHEMBL3911723 0.88 PKM (0.45) KMT2APKMKDM4EMAPTPOLB
SCHEMBL3915865 0.82 KMT2A (0.52) KMT2APKMKDM4EMAPTPOLB
SCHEMBL3916139 0.78 CYP1A2 (0.40) KMT2AKDM4EMAPTPOLBNPC1
SCHEMBL27913897 0.78 KMT2A (0.53) KMT2APKMKDM4EMAPTPOLB
SCHEMBL3908853 0.77 PKM (0.43) KMT2APKMKDM4EMAPTPOLB
SCHEMBL3912030 0.76 KMT2A (0.49) KMT2APKMKDM4EMAPTPOLB
SCHEMBL4350523 0.75 LMNA (0.43) KMT2AKDM4EPOLBNPC1RAB9A
SCHEMBL3912354 0.75 PKM (0.50) KMT2APKMKDM4EMAPTPOLB
SCHEMBL9944382 0.74 KMT2A (0.58) KMT2APKMKDM4EMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 EP disclosed