SCHEMBL3915902

SCHEMBL3915902

CCO[SiH](OCC)C(CC)OC(=O)Cc1ccncc1

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 16/20 0.54
TSHR P16473 1/20 0.39
LMNA P02545 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3911437 0.89 CYP19A1 (0.51) CYP19A1TSHRLMNAMAPT
SCHEMBL3919034 0.87 CYP19A1 (0.55) CYP19A1TSHR
SCHEMBL3912694 0.84 CYP19A1 (0.58) CYP19A1TSHRLMNAKMT2ANPSR1
SCHEMBL3910933 0.80 KMT2A (0.44) TSHRLMNAKMT2ANPSR1MAPT
SCHEMBL3915912 0.77 CYP19A1 (0.55) CYP19A1LMNAMAPT
SCHEMBL3912018 0.77 CYP19A1 (0.52) CYP19A1TSHRLMNAMAPT
SCHEMBL3911446 0.75 CYP19A1 (0.67) CYP19A1LMNAMAPT
SCHEMBL3908547 0.72 CYP19A1 (0.61) CYP19A1TSHR
SCHEMBL304656 0.72 CYP19A1 (0.63) CYP19A1TSHRMAPT
Bromide SCHEMBL11491427 0.71 CYP19A1 (0.69) CYP19A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 EP disclosed