SCHEMBL3910933

SCHEMBL3910933

CCO[SiH](OCC)C(CC)OC(=O)c1ccncc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HSD17B10 Q99714 1/20 0.40
LMNA P02545 5/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
NPC1 O15118 2/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
KDM4E B2RXH2 3/20 0.37
MAPT P10636 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3919137 0.89 KMT2A (0.42) KMT2ANPSR1HSD17B10LMNACYP1A2
SCHEMBL4350523 0.87 LMNA (0.43) KMT2ANPSR1HSD17B10LMNACYP1A2
SCHEMBL3923456 0.85 KMT2A (0.46) KMT2ANPSR1HSD17B10LMNACYP1A2
SCHEMBL3915902 0.80 CYP19A1 (0.54) KMT2ANPSR1LMNAMAPTTSHR
SCHEMBL3910944 0.75 ADRB2 (0.49) KMT2ANPSR1HSD17B10LMNAADRB2
SCHEMBL3918072 0.75 LMNA (0.41) KMT2ANPSR1HSD17B10LMNACYP1A2
SCHEMBL11641179 0.74 KMT2A (0.47) KMT2ANPSR1HSD17B10LMNACYP1A2
SCHEMBL3919146 0.73 NAMPT (0.42) KMT2ANPSR1HSD17B10LMNACYP1A2
SCHEMBL18668851 0.72 HSD17B10 (0.49) KMT2ANPSR1HSD17B10LMNACYP1A2
Formamide SCHEMBL27671692 0.71 KMT2A (0.44) KMT2ANPSR1HSD17B10LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 EP disclosed