SCHEMBL3915912

SCHEMBL3915912

CCO[SiH](OCC)C(C)COC(=O)Cc1ccncc1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 15/20 0.55
TBXAS1 P24557 1/20 0.36
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
CDC7 O00311 1/20 0.35
DBF4 Q9UBU7 1/20 0.35
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35
ADRB3 P13945 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3911446 0.87 CYP19A1 (0.67) CYP19A1TBXAS1LMNAMAPTMAPK1
SCHEMBL3919041 0.86 CYP19A1 (0.57) CYP19A1ADRB2ADRB1ADRB3
SCHEMBL3912694 0.81 CYP19A1 (0.58) CYP19A1LMNAMAPTMAPK1
SCHEMBL3910944 0.81 ADRB2 (0.49) LMNAMAPTMAPK1ADRB2ADRB1
SCHEMBL304656 0.77 CYP19A1 (0.63) CYP19A1TBXAS1MAPTCDC7DBF4
SCHEMBL3915902 0.77 CYP19A1 (0.54) CYP19A1LMNAMAPT
SCHEMBL3911437 0.75 CYP19A1 (0.51) CYP19A1LMNAMAPTMAPK1
SCHEMBL3912025 0.73 CYP19A1 (0.70) CYP19A1TBXAS1LMNAMAPTMAPK1
SCHEMBL3919146 0.70 NAMPT (0.42) CYP19A1LMNAMAPK1ADRB2ADRB1
SCHEMBL3913250 0.70 CYP19A1 (0.54) CYP19A1TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 EP disclosed