Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398239 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL4056232 | 0.95 | ALDH1A1 (0.48) | ALDH1A1THRBTSHRMGAMGAA | |
| Butane SCHEMBL9642391 | 0.93 | ALDH1A1 (0.46) | ALDH1A1THRBTSHRMGAMGAA | |
| Acetamide SCHEMBL27551278 | 0.91 | ALDH1A1 (0.44) | ALDH1A1THRBTSHRMGAMGAA | |
| Propionamide SCHEMBL27551273 | 0.88 | ALDH1A1 (0.41) | ALDH1A1THRBTSHRTDP1 | |
| Bromide SCHEMBL28301716 | 0.83 | ALDH1A1 (0.44) | ALDH1A1THRBTSHRMGAMGAA | |
| SCHEMBL7153803 | 0.80 | ALDH1A1 (0.46) | ALDH1A1THRBTSHRMGAMGAA | |
| SCHEMBL27927880 | 0.80 | MGAM (0.35) | ALDH1A1TSHRMGAMGAASI | |
| SCHEMBL15453345 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL4449709 | 0.78 | ALDH1A1 (0.44) | ALDH1A1THRBTSHRMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051861-A1 | POROUS MEMBRANE AND RECORDING MEDIA COMPRISING SAME | FUJIFILM Manufacturing Europe B.V. (NL) | 2009-04-29 | — | — | EP | disclosed |
| EP-1853430-A4 | INKJET RECORDING MEDIUM | FUJIFILM CORP (JP) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008016303-A1 | POROUS MEMBRANE AND RECORDING MEDIA COMPRISING SAME | FUJIFILM MANUFACTURING EUROPE B.V. (NL) | 2008-02-07 | — | — | WO | disclosed |
| EP-1853430-A1 | INKJET RECORDING MEDIUM | FUJIFILM Corporation (JP) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006083033-A1 | INKJET RECORDING MEDIUM | FUJIFILM CORPORATION (JP) | 2006-08-10 | — | — | WO | disclosed |