Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398239 | 0.98 | — | — | |
| Bromide SCHEMBL3916368 | 0.95 | ALDH1A1 (0.48) | ALDH1A1THRBTSHRMGAMGAA | |
| Butane SCHEMBL9642391 | 0.93 | ALDH1A1 (0.46) | ALDH1A1THRBTSHRMGAMGAA | |
| Acetamide SCHEMBL27551278 | 0.91 | ALDH1A1 (0.44) | ALDH1A1THRBTSHRMGAMGAA | |
| Propionamide SCHEMBL27551273 | 0.88 | ALDH1A1 (0.41) | ALDH1A1THRBTSHRTDP1 | |
| Hydrochloric Acid SCHEMBL4449709 | 0.83 | ALDH1A1 (0.44) | ALDH1A1THRBTSHRMGAMGAA | |
| SCHEMBL7153803 | 0.80 | ALDH1A1 (0.46) | ALDH1A1THRBTSHRMGAMGAA | |
| SCHEMBL27927880 | 0.80 | MGAM (0.35) | ALDH1A1TSHRMGAMGAASI | |
| SCHEMBL15453345 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| Bromide SCHEMBL28301716 | 0.78 | ALDH1A1 (0.44) | ALDH1A1THRBTSHRMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110981160-A | Novel composite sludge dehydrating agent and preparation and use methods thereof | 广东慧信环保有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-111499888-B | Preparation and application method of hypoxic degradable phosphorylcholine polymer nanogel | 珠海市人民医院 | 2023-01-24 | — | — | CN | disclosed |
| WO-2022044913-A1 | COATED PARTICLES AND METHOD FOR MANUFACTURING SAME | 日本化学工業株式会社 | 2022-03-03 | — | — | WO | disclosed |
| CN-112898507-A | Silicon block polymer surfactant and preparation method thereof | 广东灵捷制造化工有限公司 | 2021-06-04 | — | — | CN | disclosed |
| CN-107804905-B | Organic coagulant and preparation method thereof | 广州安达净水材料有限公司 | 2021-01-26 | — | — | CN | disclosed |
| CN-111499888-A | Preparation and application method of hypoxic degradable phosphorylcholine polymer nanogel | 珠海市人民医院 | 2020-08-07 | — | — | CN | disclosed |
| CN-107533282-A | The manufacture method and 3 D grating printed article of 3 D grating printed article | 富士胶片株式会社 | 2018-01-02 | — | — | CN | disclosed |
| EP-3189186-A1 | TEXTILE FABRIC FOR PREVENTING THE PENETRATION AND THE SPREADING OF WATER IN CABLES | Carl Freudenberg KG (DE) | 2017-07-12 | — | — | EP | disclosed |
| EP-3160412-A1 | ABSORBENT ARTICLES AND METHODS OF MAKING | 3M Innovative Properties Company (US) | 2017-05-03 | — | — | EP | disclosed |
| US-9561309-B2 | Antifouling heparin coatings | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2017-02-07 | — | — | US | disclosed |
| WO-1996032091-A2 | GEL DEODORANT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-10-17 | — | — | WO | disclosed |
| WO-1996007395-A1 | CLEAR, THICKENED TOPICAL SKIN CARE COMPOSITION WITH WATER-INSOLUBLE PERFUME | THE PROCTER & GAMBLE COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |
| EP-0469196-B1 | Terpolymer flocculants | S N F (FR) | 1995-10-11 | — | — | EP | disclosed |
| EP-0673956-A1 | Binder for coating materials containing dispersed inorganic powder, coating material containing dispersed inorganic powder, and magnetic recording medium | NIPPON ZEON CO., LTD. (JP) | 1995-09-27 | — | — | EP | disclosed |
| EP-0469196-A1 | Terpolymer flocculants | S. N. F. (FR) | 1992-02-05 | — | — | EP | disclosed |
| US-5019275-A | Acrylamide-Oxyalkyl Acrylate-Ammoniumalkyl Acrylate Terpolymer | POLYPURE, INC. (US) | 1991-05-28 | — | — | US | disclosed |
| US-4981936-A | CATIONIC FLOCCULANTS | POLYPURE, INC. (US) | 1991-01-01 | — | — | US | disclosed |
| EP-0126528-B1 | POLYMER DISPERSIONS AND THEIR PREPARATION | Ciba Specialty Chemicals Water Treatments Limited (GB) | 1988-11-30 | — | — | EP | disclosed |
| US-4528321-A | Polymer dispersions and their preparation | ALLIED COLLOIDS LIMITED (GB) | 1985-07-09 | — | — | US | disclosed |
| EP-0126528-A2 | Polymer dispersions and their preparation | Ciba Specialty Chemicals Water Treatments Limited (GB) | 1984-11-28 | — | — | EP | disclosed |