Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907346 | 0.79 | TAAR1 (0.53) | TAAR1HTR2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL30507348 | 0.79 | MGAM (0.46) | MAPTNPSR1CYP1A2 | |
| SCHEMBL3907788 | 0.79 | TAAR1 (0.49) | TAAR1HTR2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL3902047 | 0.76 | MTNR1A (0.39) | MAPT | |
| SCHEMBL3915605 | 0.76 | TAAR1 (0.58) | TAAR1HTR2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL23536662 | 0.76 | TAAR1 (0.63) | TAAR1HTR2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL3907483 | 0.75 | TAAR1 (0.52) | TAAR1HTR2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL3904582 | 0.75 | TAAR1 (0.52) | TAAR1HTR2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL25955879 | 0.74 | TAAR1 (0.51) | TAAR1MAOBHTR2A | |
| SCHEMBL3904438 | 0.73 | TAAR1 (0.55) | TAAR1MAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |