SCHEMBL3917258

SCHEMBL3917258

C=C(C)C(=O)OCCC[SiH2]C(OCCOC)OCCOC

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
THRB P10828 1/20 0.39
ALDH1A1 P00352 2/20 0.36
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL137795 0.86 TSHR (0.53) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL140539 0.85 TSHR (0.57) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL136875 0.84 TSHR (0.50) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL3914287 0.83 TSHR (0.41) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL28866107 0.83 TSHR (0.49) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL29022840 0.83 TSHR (0.54) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL27566314 0.82 TSHR (0.53) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL876650 0.82 TSHR (0.56) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL22115856 0.81 TSHR (0.59) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL16537548 0.81 TSHR (0.58) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112029088-A Silane modified polyether based on Michael addition reaction and synthesis method thereof 郑州大学 2020-12-04 CN claimed
CN-109021266-B Preparation method of filter film 长春峰泰汽车胶业有限公司 2021-02-12 CN disclosed
US-7619108-B2 Process for preparing unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2009-11-17 US disclosed
EP-1954701-B1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2009-03-18 EP disclosed
US-20080293958-A1 Process for Preparing Unsaturated Organosilicon Compounds WACKER CHEMIE AG (DE) 2008-11-27 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed
EP-1249454-A1 Preparation of unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2002-10-16 EP disclosed