Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL30070584 | 1.00 | — | — | |
| Glycine SCHEMBL3640989 | 1.00 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL30179260 | 1.00 | — | — | |
| Glycine SCHEMBL2116443 | 1.00 | — | — | |
| Glycine SCHEMBL391027 | 1.00 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL13169653 | 1.00 | — | — | |
| Glycine SCHEMBL6675874 | 1.00 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL93765 | 1.00 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL391786 | 1.00 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL29910347 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 1390525 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9976074-B2 | Self-suspending proppant particulates using canola protein-based hydrogel | HALLIBURTON ENERGY SERVICES, INC. (US) | 2018-05-22 | — | — | US | claimed |
| US-9975940-B2 | Long-acting single-chain insulin analogues | CASE WESTERN RESERVE UNIVERSITY (US) | 2018-05-22 | — | — | US | claimed |
| US-9976126-B2 | Modified glycine oxidase | AJINOMOTO CO., INC. (JP) | 2018-05-22 | — | — | US | claimed |
| US-9979011-B2 | LixMn2O4-y(C1z) spinal cathode material, method of preparing the same, and rechargeable lithium and li-ion electrochemical systems containing the same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2018-05-22 | — | — | US | claimed |
| US-9976077-B2 | Photochromic articles containing polyoxometalate derivatives and methods of making same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-05-22 | — | — | US | claimed |
| US-9976111-B2 | TiN hard mask and etch residual removal | VERSUM MATERIALS US, LLC (US) | 2018-05-22 | — | — | US | claimed |
| US-9974728-B2 | Cosmetic composition comprising a synergistic TRF2 protein activation system consisting of a combination of a peptidic soybean and yeast extract and the uses thereof | ISP INVESTMENTS LLC (US) | 2018-05-22 | — | — | US | claimed |
| US-9974851-B2 | Human rotavirus vaccine strains and diagnostics | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-05-22 | — | — | US | claimed |
| US-9975107-B2 | Multi-scaled oxygen storage material based on ceria-zirconia having high oxygen storage and releasing ability and a preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2018-05-22 | — | — | US | claimed |
| US-9978609-B2 | Low dishing copper chemical mechanical planarization | VERSUM MATERIALS US, LLC (US) | 2018-05-22 | — | — | US | claimed |
| US-3979354-A | EPOXY RESINS, ORGANOTIN CROSSLINKING AGENT | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1976-09-07 | — | — | US | claimed |
| US-3971700-A | Process for the enzymatic resolution of DL-phenyl glycine amide into its optically active antipodes | STAMICARBON B.V. (NL) | 1976-07-27 | — | — | US | claimed |
| US-3966703-A | Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | claimed |
| US-3963527-A | Chromatizing process and composition | LINDEMANN & CO. GMBH (DT) | 1976-06-15 | — | — | US | claimed |
| US-3960835-A | RUMINANT GROWTH PROMOTER | COMMERCIAL SOLVENTS CORPORATION (US) | 1976-06-01 | — | — | US | claimed |
| US-3958581-A | Cosmetic composition containing a cationic polymer and divalent metal salt for strengthening the hair | L'OREAL (FR) | 1976-05-25 | — | — | US | claimed |
| US-3957587-A | MUTANT STRAIN OF SPREPTOMYCES | CPC INTERNATIONAL INC. (US) | 1976-05-18 | — | — | US | claimed |
| US-3951748-A | Sensitized matrix for detection of disease | MEDICAL PRODUCTS, INC. (US) | 1976-04-20 | — | — | US | claimed |
| US-3939098-A | Suspension for depositing a pyroelectric material | RCA CORPORATION (US) | 1976-02-17 | — | — | US | claimed |
| US-3933783-A | Formation of peptide bonds in the presence of isonitriles | AJINOMOTO CO., INC. (JA) | 1976-01-20 | — | — | US | claimed |