SCHEMBL3918341

SCHEMBL3918341

COc1ccc(C(OC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)[C@H](OCCC#N)[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.48
P2RY2 P41231 12/20 0.48
P2RY4 P51582 5/20 0.48
P2RY14 Q15391 4/20 0.48
P2RY6 Q15077 7/20 0.42
P2RY12 Q9H244 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13715991 1.00 TYMP (0.48) TYMPP2RY2P2RY4P2RY14P2RY6
SCHEMBL3918343 1.00 TYMP (0.48) TYMPP2RY2P2RY4P2RY14P2RY6
SCHEMBL2108638 0.96 TYMP (0.46) TYMPP2RY2P2RY4P2RY14P2RY6
SCHEMBL2108637 0.96 TYMP (0.46) TYMPP2RY2P2RY4P2RY14P2RY6
SCHEMBL15841327 0.94 TYMP (0.45) TYMPP2RY2P2RY4P2RY14P2RY6
SCHEMBL19971896 0.94 TYMP (0.45) TYMPP2RY2P2RY4P2RY14P2RY6
SCHEMBL15841328 0.94 TYMP (0.45) TYMPP2RY2P2RY4P2RY14P2RY6
SCHEMBL7553293 0.91 TYMP (0.51) TYMPP2RY2P2RY4P2RY14P2RY6
SCHEMBL4451613 0.91 TYMP (0.51) TYMPP2RY2P2RY4P2RY14P2RY6
SCHEMBL6831398 0.91 TYMP (0.51) TYMPP2RY2P2RY4P2RY14P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569685-B2 Artificial RNAóS modified at the 2ó-hydroxyl group JAPAN SCIENCCE AND TECHNOLOGY AGENCY (JP) 2009-08-04 US disclosed
US-20080021206-A1 Novel Artificial Rnaos Modified At The 2o-Hydroxyl Group JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2008-01-24 US disclosed
EP-1726597-A1 NOVEL ARTIFICIAL RNAóS MODIFIED AT THE 2ó-HYDROXYL GROUP Japan Science and Technology Agency (JP) 2006-11-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080021206-A1 Novel Artificial Rnaos Modified At The 2o-Hydroxyl Group FBL, NSUN2, METTL16 TYMP 826/4885P2RY2 1196/4885P2RY4 1747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.