Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.57 |
| ▸ | RXRA | P19793 | 3/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | RXRG | P48443 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798873 | 0.90 | GLRA1 (0.58) | GLRA1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL3925722 | 0.89 | GLRA1 (0.71) | GLRA1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL10256639 | 0.85 | ELANE (0.53) | GLRA1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL16641909 | 0.83 | GLRA1 (0.67) | GLRA1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL22480760 | 0.83 | MRGPRX4 (0.73) | MRGPRX4MEN1KMT2ANPC1HPGD | |
| SCHEMBL16860678 | 0.82 | GLRA1 (0.79) | GLRA1MRGPRX4RXRARXRBNR4A2 | |
| SCHEMBL11890579 | 0.82 | MRGPRX4 (0.46) | GLRA1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL8800593 | 0.82 | GLRA1 (0.50) | GLRA1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL17037217 | 0.82 | MRGPRX4 (0.56) | MRGPRX4RXRARXRBRXRGNR4A2 | |
| SCHEMBL8801048 | 0.82 | FFAR4 (0.51) | GLRA1RXRARXRBRXRGPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176841-A1 | NOVEL 6-5 SYSTEM BICYCLIC HETEROCYCLIC DERIVATIVE AND ITS PHARMACEUTICAL UTILITY | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2036887-A1 | NOVEL 6-5 BICYCIC HETEROCYCLIC DERIVATIVE AND MEDICAL USE THEREOF | Sanwa Kagaku Kenkyusho Co., Ltd (JP) | 2009-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176841-A1 | NOVEL 6-5 SYSTEM BICYCLIC HETEROCYCLIC DERIVATIVE AND ITS PHARMACEUTICAL UTILITY | TSHR, TRHR, THRA | GLRA1 383/4885MRGPRX4 169/4885RXRA 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.