Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xylitol SCHEMBL6240620 | 0.78 | LMNA (0.71) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Adonitol SCHEMBL28031758 | 0.78 | LMNA (0.71) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Xylitol SCHEMBL5306386 | 0.78 | LMNA (0.83) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Ribitol SCHEMBL8182152 | 0.78 | LMNA (0.83) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Xylitol SCHEMBL13080875 | 0.78 | LMNA (0.83) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Xylitol SCHEMBL4599492 | 0.78 | LMNA (0.83) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Xylitol SCHEMBL1924966 | 0.78 | LMNA (0.83) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Adonitol SCHEMBL20594035 | 0.78 | LMNA (0.83) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Adonitol SCHEMBL22572531 | 0.78 | LMNA (0.83) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Xylitol SCHEMBL5273838 | 0.78 | LMNA (0.83) | LMNAL3MBTL1TDP1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924684-A4 | TRANSITION STATE STRUCTURE OF 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASES | EINSTEIN COLL MED (US) | 2009-02-11 | — | — | EP | disclosed |
| EP-1924684-A2 | TRANSITION STATE STRUCTURE OF 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASES | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, a division of YESHIVA UNIVERSITY (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007016291-A2 | TRANSITION STATE STRUCTURE OF 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASES | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2007-02-08 | — | — | WO | disclosed |