Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15711280 | 1.00 | HTT (0.44) | HTTTSHRL3MBTL1SMN1; SMN2RECQL | |
| SCHEMBL6159138 | 1.00 | HTT (0.44) | HTTTSHRL3MBTL1SMN1; SMN2RECQL | |
| SCHEMBL11797788 | 0.86 | HTT (0.42) | HTTTSHRL3MBTL1SMN1; SMN2RECQL | |
| SCHEMBL5799729 | 0.84 | HTT (0.46) | HTTTSHRL3MBTL1SMN1; SMN2RECQL | |
| SCHEMBL21504066 | 0.84 | SMN1; SMN2 (0.48) | HTTTSHRL3MBTL1SMN1; SMN2RECQL | |
| SCHEMBL6454206 | 0.83 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL15710681 | 0.83 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL15710677 | 0.83 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL15710535 | 0.81 | F2 (0.40) | L3MBTL1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL6157884 | 0.81 | F2 (0.40) | L3MBTL1LMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425590-B1 | PROCESS FOR STABILISING THE pH OF AQUEOUS FEED SOLUTIONS AND FOR ABSORBING AND BUFFERING URINE AND WOUND SECRETIONS | MARIGEN SA (CH) | 1993-12-15 | — | — | EP | claimed |
| EP-1888213-B1 | FLUIDICS DEVICE | BIO RAD LABORATORIES INC (US) | 2017-10-18 | — | — | EP | disclosed |
| US-20160257686-A1 | Purinone Derivatives as Tyrosine Kinase Inhibitors | PRINCIPIA BIOPHARMA INC. (US) | 2016-09-08 | — | — | US | disclosed |
| US-20140142099-A1 | Purinone Derivatives as Tyrosine Kinase Inhibitors | PRINCIPIA BIOPHARMA INC. (US) | 2014-05-22 | — | — | US | disclosed |
| US-8491791-B2 | Fluidics device | BIO-RAD LABORATORIES, INC. (US) | 2013-07-23 | — | — | US | disclosed |
| US-20120309644-A1 | FLUIDICS DEVICE | BIO-RAD LABORATORIES, INC. (US) | 2012-12-06 | — | — | US | disclosed |
| US-8246832-B2 | Fluidics device | BIO-RAD LABORATORIES, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| US-20090179146-A1 | FLUIDICS DEVICE | BIO-RAD LABORATORIES, INC. | 2009-07-16 | — | — | US | disclosed |
| EP-1888213-A2 | FLUIDICS DEVICE | Bio-Rad Laboratories, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006127056-A2 | FLUIDICS DEVICE | BIO-RAD LABORATORIES, INC. (US) | 2006-11-30 | — | — | WO | disclosed |
| US-4009195-A | FROM 1-ALKENES AND ACRYLIC ACID DERIVATIVES | ROHM AND HAAS COMPANY (US) | 1977-02-22 | — | — | US | disclosed |
| US-3994958-A | OF 1-ALKENES AND ACRYLIC ACID DERIVATIVES | ROHM AND HAAS COMPANY (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142099-A1 | Purinone Derivatives as Tyrosine Kinase Inhibitors | BMX, BLK, ITK | HTT 2657/4885TSHR 2007/4885L3MBTL1 4862/4885 |
| US-20160257686-A1 | Purinone Derivatives as Tyrosine Kinase Inhibitors | BMX, BLK, ITK | HTT 2657/4885TSHR 2007/4885L3MBTL1 4862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.