SCHEMBL6159138

SCHEMBL6159138

CC/C=C(\C(N)=O)N1CCOCC1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.44
TSHR P16473 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
RECQL P46063 1/20 0.41
POLB P06746 3/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 2/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MEN1 O00255 1/20 0.37
TP53 P04637 1/20 0.37
KMT2A Q03164 1/20 0.37
RAB9A P51151 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15711280 1.00 HTT (0.44) HTTTSHRL3MBTL1SMN1; SMN2RECQL
SCHEMBL3919626 1.00 HTT (0.44) HTTTSHRL3MBTL1SMN1; SMN2RECQL
SCHEMBL11797788 0.86 HTT (0.42) HTTTSHRL3MBTL1SMN1; SMN2RECQL
SCHEMBL5799729 0.84 HTT (0.46) HTTTSHRL3MBTL1SMN1; SMN2RECQL
SCHEMBL21504066 0.84 SMN1; SMN2 (0.48) HTTTSHRL3MBTL1SMN1; SMN2RECQL
SCHEMBL6454206 0.83 L3MBTL1 (0.37) L3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL15710681 0.83 L3MBTL1 (0.37) L3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL15710677 0.83 L3MBTL1 (0.37) L3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL15710535 0.81 F2 (0.40) L3MBTL1LMNAALDH1A1MEN1KMT2A
SCHEMBL6157884 0.81 F2 (0.40) L3MBTL1LMNAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1539846-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS Applera Corporation (US) 2005-06-15 EP claimed
EP-1504044-A2 CORE-SHELL POLYMERIC COMPOSITIONS MEADWESTVACO CORPORATION, Law Department (US) 2005-02-09 EP claimed
US-6767638-B2 Core-shell polymeric compositions MEADWESTVACO CORPORATION 2004-07-27 US claimed
WO-2004011513-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS APPLERA CORPORATION (US) 2004-02-05 WO claimed
WO-2003097709-A2 CORE-SHELL POLYMERIC COMPOSITIONS MEADWESTVACO CORPORATION (US) 2003-11-27 WO claimed
US-20030215604-A1 Core-shell polymeric compositions WESTVACO CORPORATION (US) 2003-11-20 US claimed
EP-0296926-B1 COMPOSITE POLYMERS, THEIR PREPARATION AND THEIR USE IN LIQUID CHROMATOGRAPHY I.B.F. (FR) 1992-10-14 EP claimed
US-5075371-A COMPOSITE POLYMERS AND THEIR PREPARATION WHICH ARE USEFUL IN LIQUID CHROMATOGRAPHY I.B.F. (FR) 1991-12-24 US claimed
US-5053135-A COMPOSITE POLYMERS, THEIR PREPARATION AND THEIR USE IN LIQUID CHROMATOGRAPHY I.B.F. (FR) 1991-10-01 US claimed
EP-0296926-A1 Composite polymers, their preparation and their use in liquid chromatography I.B.F. (FR) 1988-12-28 EP claimed
EP-1539846-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS Applera Corporation (US) 2005-06-15 EP disclosed
EP-1504044-A2 CORE-SHELL POLYMERIC COMPOSITIONS MEADWESTVACO CORPORATION, Law Department (US) 2005-02-09 EP disclosed
EP-1353992-B1 NOVEL POLYMER BINDER SYSTEMS COMPRISING IONIC LIQUIDS CREAVIS GES FUER TECHNOLOGIEUN (DE) 2005-02-09 EP disclosed
US-6767638-B2 Core-shell polymeric compositions MEADWESTVACO CORPORATION 2004-07-27 US disclosed
US-20040054041-A1 NOVEL POLYMER BINDER SYSTEMS COMPRISING IONIC LIQUIDS DEGUSSA AG (DE) 2004-03-18 US disclosed
EP-0296926-B1 COMPOSITE POLYMERS, THEIR PREPARATION AND THEIR USE IN LIQUID CHROMATOGRAPHY I.B.F. (FR) 1992-10-14 EP disclosed
US-5075371-A COMPOSITE POLYMERS AND THEIR PREPARATION WHICH ARE USEFUL IN LIQUID CHROMATOGRAPHY I.B.F. (FR) 1991-12-24 US disclosed
US-5053135-A COMPOSITE POLYMERS, THEIR PREPARATION AND THEIR USE IN LIQUID CHROMATOGRAPHY I.B.F. (FR) 1991-10-01 US disclosed
EP-0415055-A2 Water-soluble pressure-sensitive skin adhesive RÖHM GMBH (DE) 1991-03-06 EP disclosed
US-3957492-A Photographic silver halide emulsion comprising an amphoteric copolymer FUJI PHOTO FILM CO., LTD. (JA) 1976-05-18 US disclosed