SCHEMBL391963

SCHEMBL391963

CCCCCCCCCCCCCCCCCC[Ti](CCCCCCCCCCCCCCCCCC)(CCCCCCCCCCCCCCCCCC)CCCCCCCCCCCCCCCCCC

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
THRB P10828 1/20 0.57
DNM1 Q05193 7/20 0.42
ALDH1A1 P00352 3/20 0.42
LMNA P02545 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HSD17B10 Q99714 1/20 0.42
SLC22A1 O15245 1/20 0.42
EPHX1 P07099 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11053786 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL1203585 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL433626 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9243081 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL15194653 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL1602019 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL7596192 0.96 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL129869 0.85 TSHR (0.46) TSHRTHRBDNM1ALDH1A1LMNA
Bromide SCHEMBL31355455 0.81 TSHR (0.43) TSHRTHRBDNM1ALDH1A1LMNA
Water SCHEMBL5691760 0.81 TSHR (0.43) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4461867-A CONTAINING A DIORGANOCYCLOPOLYSILOXANE COMPOUND GENERAL ELECTRIC COMPANY (US) 1984-07-24 US claimed
WO-2025023022-A1 RESIN COMPOSITION, OPTICAL FILTER, AND METHOD FOR MANUFACTURING OPTICAL FILTER 株式会社日本触媒 2025-01-30 WO disclosed
CN-115190891-B Curable resin composition, cured film, laminate, method for producing cured film, and semiconductor device 富士胶片株式会社 2024-10-15 CN disclosed
CN-118459741-A Polyester-based glycidyl ether and preparation method and application thereof 南京林业大学 2024-08-09 CN disclosed
CN-118435349-A Method for producing joined body, method for producing laminate, method for producing device, and composition for forming polyimide-containing precursor portion 富士胶片株式会社 2024-08-02 CN disclosed
CN-115667404-B Curable resin composition, cured film, laminate, method for producing cured film, and semiconductor device 富士胶片株式会社 2024-05-03 CN disclosed
EP-3662020-B1 DUAL CURABLE SILICONE COMPOSITIONS DOW SILICONES CORP (US) 2022-01-26 EP disclosed
US-11028286-B2 Dual curable silicone compositions DOW SILICONES CORPORATION (US) 2021-06-08 US disclosed
US-20200199403-A1 DUAL CURABLE SILICONE COMPOSITIONS DOW SILICONES CORPORATION 2020-06-25 US disclosed
EP-3662020-A1 DUAL CURABLE SILICONE COMPOSITIONS Dow Silicones Corporation (US) 2020-06-10 EP disclosed
US-4388437-A CREASE RESISTANCE, SOFTNESS, RESILIENCE, AND WATER REPELLENCY TO FIBERS TORAY SILICONE COMPANY, LTD. (JP) 1983-06-14 US disclosed
WO-1983000156-A1 ONE PACKAGE, STABLE, MOISTURE CURABLE, POLYALKOXY-TERMINATED ORGANOPOLYSILOXANE COMPOSITIONS AND METHOD FOR MAKING GEN ELECTRIC (US) 1983-01-20 WO disclosed
EP-0069256-A2 One package, stable, moisture curable, polyalkoxy-terminated organopolysiloxane compositions and method for making GENERAL ELECTRIC COMPANY (US) 1983-01-12 EP disclosed
EP-0055606-A1 Amino-functional silicone emulsions Toray Silicone Company Limited (JP) 1982-07-07 EP disclosed
US-4332844-A ALKOXY-CONTAINING SILICON COMPOUND, ORGANOTITANATE, AND ORGANOHYDROGENSILICON COMPOUND TORAY SILICONE LIMITED (JP) 1982-06-01 US disclosed
EP-0031994-A2 Organopolysiloxanes that contain sulfur and curable compositions including the same DOW CORNING CORPORATION (US) 1981-07-15 EP disclosed
WO-1981001561-A1 MERCAPTOORGANOPOLYSILOXANES AND CURABLE COMPOSITIONS INCLUDING SAME DOW CORNING (US) 1981-06-11 WO disclosed
US-4269963-A POLYDIMETHYLSILOXANE ENDCAPPED WITH TRIMETHYLSILANOL AND A SULFIDE-CONTAINING SILANDIOL OR -TRIOL; STORAGE STABILITY; SEALANTS, CAULKING, AND DIELECTRICS; MOISTURE-CURED DOW CORNING CORPORATION (US) 1981-05-26 US disclosed
US-RE29760-E RUBBER FOR COATING, SEALANT OR CAULK DOW CORNING CORPORATION (US) 1978-09-12 US disclosed
US-3997496-A Process for the preparation of fluorosilicone polymers and copolymers GENERAL ELECTRIC COMPANY (US) 1976-12-14 US disclosed