Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31035861 | 0.98 | TRPV1 (0.73) | TRPV1HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL31035980 | 0.98 | TRPV1 (0.73) | TRPV1HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL31036003 | 0.98 | TRPV1 (0.73) | TRPV1HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7598872 | 0.95 | L3MBTL1 (0.74) | TRPV1HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL25139566 | 0.89 | L3MBTL1 (0.66) | TRPV1HPGDKMT2AALDH1A1L3MBTL1 | |
| Benzene SCHEMBL29176463 | 0.87 | MTNR1A (0.73) | HPGDALDH1A1L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL154367 | 0.87 | MTNR1A (0.73) | HPGDALDH1A1L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL15598268 | 0.87 | HPGD (0.77) | TRPV1HPGDKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL10106175 | 0.85 | L3MBTL1 (0.61) | TRPV1HPGDKMT2AL3MBTL1GAA | |
| SCHEMBL15550290 | 0.85 | HDAC3 (0.72) | HPGDL3MBTL1LMNATSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038267-A2 | THIADIAZOLIDINONE INHIBITORS OF PTPASE | Novartis AG (CH) | 2009-03-25 | — | — | EP | claimed |
| WO-2007115058-A2 | THIADIAZOLIDINONE INHIBITORS OF PTPASE | NOVARTIS AG (CH) | 2007-10-11 | — | — | WO | claimed |
| EP-2038267-A2 | THIADIAZOLIDINONE INHIBITORS OF PTPASE | Novartis AG (CH) | 2009-03-25 | — | — | EP | disclosed |
| WO-2007115058-A2 | THIADIAZOLIDINONE INHIBITORS OF PTPASE | NOVARTIS AG (CH) | 2007-10-11 | — | — | WO | disclosed |
| US-7226906-B2 | Cyclosporin analogs for the treatment of immunoregulatory disorders and respiratory diseases | ARRAY BIOPHARMA, INC. (US) | 2007-06-05 | — | — | US | disclosed |
| EP-1254114-A2 | MELANOCORTIN RECEPTOR AGONISTS AND ANTAGONISTS | Melacure Therapeutics AB (SE) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055106-A2 | NOVEL MELANOCORTIN RECEPTOR AGONISTS AND ANTAGONISTS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | disclosed |