SCHEMBL3919920

SCHEMBL3919920

CCO[Si](CC(=O)CC(C)=O)(OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 1/20 0.37
KDM6B O15054 1/20 0.37
KDM5C P41229 1/20 0.37
EGLN1 Q9GZT9 1/20 0.37
PHF8 Q9UPP1 1/20 0.37
KDM2A Q9Y2K7 1/20 0.37
MGAM O43451 2/20 0.36
GAA P10253 2/20 0.36
SI P14410 2/20 0.36
MGAM2 Q2M2H8 2/20 0.36
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28132688 0.81 ALDH1A1 (0.45) ALDH1A1TDP1MGAMGAASI
SCHEMBL3919588 0.81 KDM4E (0.35) ALDH1A1TDP1KDM4EKDM6BKDM5C
SCHEMBL2006528 0.79 KDM4E (0.43) ALDH1A1TDP1KDM4EKDM6BKDM5C
SCHEMBL3910773 0.77 MGAM (0.44) ALDH1A1KDM4EKDM6BKDM5CEGLN1
SCHEMBL15397840 0.76 KDM4E (0.41) ALDH1A1TDP1KDM4EKDM6BKDM5C
SCHEMBL3912265 0.73 TSHR (0.42) ALDH1A1KDM4EMGAMGAASI
SCHEMBL1093452 0.72 FFAR3 (0.38) ALDH1A1TDP1EGLN1MGAMGAA
SCHEMBL29067008 0.71 MGAM (0.43) ALDH1A1TDP1MGAMGAASI
SCHEMBL3920887 0.70 GAA (0.52) ALDH1A1MGAMGAASIMGAM2
SCHEMBL19194876 0.70 ALOX15 (0.40) ALDH1A1TDP1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 EP disclosed