Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.42 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29572246 | 1.00 | IDO1 (0.48) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| Carbamic Acid SCHEMBL11788382 | 0.87 | HTR3E (0.51) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL364144 | 0.81 | HSD11B1 (0.44) | IDO1NOTUMHSD11B1 | |
| SCHEMBL18167293 | 0.81 | TSHR (0.43) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL29435960 | 0.81 | HSD11B1 (0.44) | IDO1NOTUMHSD11B1 | |
| SCHEMBL803635 | 0.79 | PTGS1 (0.39) | IDO1HSD11B1 | |
| SCHEMBL29649700 | 0.78 | IDO1 (0.50) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL2698021 | 0.78 | NOTUM (0.61) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL987352 | 0.78 | IDO1 (0.50) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7601736 | 0.77 | IDO1 (0.50) | IDO1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113277942-B | Method for rapidly preparing 5-chloro-2-fluoro-4- (trifluoromethyl) benzoic acid based on microchannel reaction technology | 都创(上海)医药开发有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-113277942-A | Method for rapidly preparing 5-chloro-2-fluoro-4- (trifluoromethyl) benzoic acid based on microchannel reaction technology | 都创(上海)医药开发有限公司 | 2021-08-20 | — | — | CN | claimed |
| CN-112058115-A | Stirring and filtering integrated device for preparing 2-chloro-5-fluorobenzotrifluoride | 上海思阔化学科技有限公司 | 2020-12-11 | — | — | CN | claimed |
| US-4603222-A | Method for the preparation of nitrodiphenyl ethers | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-07-29 | — | — | US | claimed |
| EP-0173349-A1 | Method for the preparation of nitrodiphenyl ethers | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-03-05 | — | — | EP | claimed |
| EP-0159388-A2 | Preparation of nuclear chlorinated compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1985-10-30 | — | — | EP | claimed |
| US-4470930-A | Preparation of nuclear chlorinated aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-09-11 | — | — | US | claimed |
| US-4469893-A | Method for the preparation of nitrodiphenyl ethers | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-09-04 | — | — | US | claimed |
| US-4424396-A | ARYL HALIDE, A-AMINOACID | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-01-03 | — | — | US | claimed |
| JP-62289534-A | — | — | None | — | — | JP | disclosed |
| EP-4583867-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | Latigo Biotherapeutics, Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024217344-A1 | NAV1.8 INHIBITORS, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2024-10-24 | — | — | WO | disclosed |
| CN-118324743-A | Nav1.8 inhibitor and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-07-12 | — | — | CN | disclosed |
| CN-114437062-B | Compound capable of being used as sodium channel regulator and application thereof | 成都海博为药业有限公司 | 2024-05-17 | — | — | CN | disclosed |
| EP-0159388-A2 | Preparation of nuclear chlorinated compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1985-10-30 | — | — | EP | disclosed |
| EP-0125803-A2 | Pharmaceutically active dihydropyridines | FISONS plc (GB) | 1984-11-21 | — | — | EP | disclosed |
| US-4470930-A | Preparation of nuclear chlorinated aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-09-11 | — | — | US | disclosed |
| US-4469893-A | Method for the preparation of nitrodiphenyl ethers | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-09-04 | — | — | US | disclosed |
| US-4424396-A | ARYL HALIDE, A-AMINOACID | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |
| EP-0095117-A1 | Phenoxypropionic-acid derivatives, processes for their preparation and their use as herbicides | BAYER AG (DE) | 1983-11-30 | — | — | EP | disclosed |