SCHEMBL392087

SCHEMBL392087

CC(C)(CO)C(=O)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
ALDH1A1 P00352 1/20 0.40
HMGCR P04035 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
ADRA1A P35348 1/20 0.33
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
OR51E2 Q9H255 1/20 0.32
TET2 Q6N021 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13176677 0.78 TET2 (0.33) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL166880 0.77 TSHR (0.40) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL38932 0.75
SCHEMBL8664625 0.75 TSHR (0.44) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL13038657 0.74 KDM4E (0.42) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL7976063 0.74 TSHR (0.38) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL15105881 0.74 TSHR (0.38) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL728692 0.74 HMGCR (0.50) TSHRALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL979789 0.73
SCHEMBL1765014 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022409-A1 PANTOIC ACID-PRODUCING RECOMBINANT MICROORGANISM AND USE THEREOF ANHUI HUAHENG BIOTECHNOLOGY CO LTD (CN) 2026-01-22 US claimed
EP-4674950-A1 RECOMBINANT MICROORGANISM FOR PRODUCING PANTOIC ACID AND USE THEREOF Anhui Huaheng Biotechnology Co., Ltd. (CN) 2026-01-07 EP claimed
CN-119842656-A Preparation and application of ketopantoic acid hydroxymethyl transferase mutant for D-pantothenic acid production 江南大学 2025-04-18 CN claimed
CN-119709733-A Dynamic regulation system, pantoic acid production strain, preparation method and application thereof 安徽华恒生物科技股份有限公司 2025-03-28 CN claimed
CN-118871565-A Novel lipid peroxidation system and method for preparing biofuel and biopolymer using the same 韩国科学技术院 2024-10-29 CN claimed
CN-118813431-A Microorganism and application thereof 武汉大学 2024-10-22 CN claimed
CN-115058401-B Ketopantoic acid hydroxymethyl transferase mutant, coding gene and application 浙江工业大学 2024-07-12 CN claimed
WO-2024114333-A1 An enzyme catalyst and method for synthesizing D-pantoic acid ENZYMASTER (NINGBO) BIO-ENGINEERING CO., LTD. (CN) 2024-06-06 WO claimed
CN-118086235-A Enzyme catalyst and method for synthesizing D-pantoic acid 宁波酶赛生物工程有限公司 2024-05-28 CN claimed
CN-117802064-A Ketone pantoic acid hydroxymethyl transferase mutant, coding gene and application 浙江工业大学 2024-04-02 CN claimed
EP-2707475-A1 PRODUCTION OF ACETYL-COENZYME A DERIVED COMPOUNDS Amyris, Inc. (US) 2014-03-19 EP claimed
US-8494779-B2 Method for screening essential metabolites in growth of microorganisms KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-07-23 US claimed
WO-2012154854-A1 PRODUCTION OF ACETYL-COENZYME A DERIVED COMPOUNDS Amyris, Inc. (US) 2012-11-15 WO claimed
US-20120288891-A1 PRODUCTION OF ACETYL-COENZYME A DERIVED COMPOUNDS Amyris, Inc. (US) 2012-11-15 US claimed
WO-2011034263-A1 METHOD FOR PREDICTING A DRUG TARGET IN PATHOGENIC MICROORGANISMS USING AN ESSENTIAL METABOLITE 한국과학기술원 (KR) 2011-03-24 WO claimed
WO-2011034397-A2 METHOD FOR PREDICTING DRUG TARGETS AND SCREENING FOR DRUGS FOR PATHOGENIC MICROORGANISMS USING ESSENTIAL METABOLITES 한국과학기술원 (KR) 2011-03-24 WO claimed
US-20100143911-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2010-06-10 US claimed
EP-2097743-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS Korea Advanced Institute of Science and Technology (KR) 2009-09-09 EP claimed
WO-2008078911-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-07-03 WO claimed
WO-2001077366-A1 POSITIVE SELECTION METHOD, COMPOUNDS, HOST CELLS AND USES THEREOF CUBIST PHARMACEUTICALS, INC. (US) 2001-10-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022409-A1 PANTOIC ACID-PRODUCING RECOMBINANT MICROORGANISM AND USE THEREOF COASY, PGAM1, ME1 TSHR 2460/4885ALDH1A1 549/4885HMGCR 178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.