Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19406521 | 0.91 | ALDH1A1 (0.41) | ALDH1A1EPHX1CYP1A2TSHRTHRB | |
| SCHEMBL8749582 | 0.90 | — | — | |
| SCHEMBL20873648 | 0.89 | ALDH1A1 (0.40) | ALDH1A1EPHX1CYP1A2TSHRTHRB | |
| SCHEMBL28756382 | 0.84 | EPHX1 (0.42) | ALDH1A1EPHX1CYP1A2TSHRTHRB | |
| SCHEMBL6718471 | 0.84 | EPHX1 (0.42) | ALDH1A1EPHX1CYP1A2TSHRTHRB | |
| SCHEMBL25269130 | 0.84 | EPHX1 (0.42) | ALDH1A1EPHX1CYP1A2TSHRTHRB | |
| SCHEMBL27871414 | 0.82 | CYP1A2 (0.42) | ALDH1A1EPHX1CYP1A2TSHRTHRB | |
| SCHEMBL293603 | 0.82 | ALDH1A1 (0.35) | ALDH1A1EPHX1CYP1A2ALOX5SPHK1 | |
| SCHEMBL2369990 | 0.81 | CYP1A2 (0.43) | ALDH1A1EPHX1CYP1A2LSSMEN1 | |
| SCHEMBL294406 | 0.79 | CYP1A2 (0.33) | ALDH1A1EPHX1CYP1A2ALOX5SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1507761-B1 | PYRIDINE CARBOXAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | MERIAL INC (US) | 2016-02-24 | — | — | EP | disclosed |
| US-7629348-B2 | Heterocyclic amide and imine derivatives, processes for their preparation, compositions comprising them and their use as pesticides | MERIAL LIMITED (US) | 2009-12-08 | — | — | US | disclosed |
| CN-100548987-C | Parasiticidal derivative of pyridine carboxamide | BAYER CROPSCIENCE GMBH (DE) | 2009-10-14 | — | — | CN | disclosed |
| US-7560456-B2 | Pesticidal pyridinecarboxamide derivatives | MERIAL LIMITED (US) | 2009-07-14 | — | — | US | disclosed |
| US-7476685-B2 | Pyridine carboxamide derivatives and their use as pesticides | MERIAL LIMITED (US) | 2009-01-13 | — | — | US | disclosed |
| CN-101230038-A | Pyridine carboxamide derivatives and their use as pesticides | BAYER CROPSCIENCE GMBH (DE) | 2008-07-30 | — | — | CN | disclosed |
| US-20080139627-A1 | Heterocyclic amide and imine derivatives, processes for their preparation, compositions comprising them and their use as pesticides | BECKMANN MARION | 2008-06-12 | — | — | US | disclosed |
| US-20080097099-A1 | Heterocyclic amide and imine derivatives, processes for their preparation, compositions comprising them and their use as pesticides | BECKMANN MARION | 2008-04-24 | — | — | US | disclosed |
| CN-100378076-C | Pyridinecarboxamide derivatives and their use as pesticides | BAYER CROPSCIENCE GMBH (DE) | 2008-04-02 | — | — | CN | disclosed |
| EP-1432313-B1 | N-THIO-NICOTINAMIDE DERIVATIVES AND RELATED COMPOUNDS FOR USE AS PESTICIDES | MERIAL LTD (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2001070692-A2 | HETEROCYCLIC ACYLSULFIMIDES, A METHOD FOR THEIR PRODUCTION, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2001-09-27 | — | — | WO | disclosed |
| US-6239160-B1 | 4-haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclylpyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | HOECHST SCHERING AGREVO GMBH (DE) | 2001-05-29 | — | — | US | disclosed |
| EP-1083795-A2 | METHOD FOR CONTROLLING PESTS IN CROP CULTURES | Aventis CropScience GmbH (DE) | 2001-03-21 | — | — | EP | disclosed |
| CN-1260793-A | 4-haloalkyl-3-heterocyclyl pyridines and 4-haloalkyl-5-heterocyclyl pyrimidines, method for the production thereof, agents containing the same and use thereof as pesticides | HOECHST SCHERING AGREVO GMBH (DE) | 2000-07-19 | — | — | CN | disclosed |
| WO-2000035912-A1 | 4-TRIFLUOROMETHYL-3-OXAZOLYLPYRIDINES, METHOD FOR PRODUCING THEM, PRODUCTS CONTAINING THE SAME, AND THEIR USE AS PESTICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 2000-06-22 | — | — | WO | disclosed |
| WO-2000035285-A1 | 4-HALOALKYL-3-HETEROCYCLYLPYRIDINES AND 4-HALOALKYL-5-HETEROCYCLYL-PYRIMIDINES AND THEIR USE AS REPELLENTS | AVENTIS CROPSCIENCE GMBH (DE) | 2000-06-22 | — | — | WO | disclosed |
| WO-2000035913-A1 | 4-TRIFLUOROMETHYL-3-OXADIAZOLYL PYRIDINES, METHODS FOR THE PRODUCTION THEREOF, AGENTS CONTAINING THESE COMPOUNDS, AND THEIR USE AS PESTICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 2000-06-22 | — | — | WO | disclosed |
| EP-0991648-A1 | 4-HALOALKYL-3- HETEROCYCLYLPYRIDINES AND 4-HALOALKYL -5-HETEROCYCLYLPYRIDINES, METHOD FOR THE PRODUCTION THEREOF, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999063829-A2 | METHOD FOR CONTROLLING PESTS IN BT COTTON CULTURES | AVENTIS CROPSCIENCE GMBH (DE) | 1999-12-16 | — | — | WO | disclosed |
| WO-1998057969-A1 | 4-HALOALKYL-3- HETEROCYCLYLPYRIDINES AND 4-HALOALKYL -5-HETEROCYCLYLPYRIDINES, METHOD FOR THE PRODUCTION THEREOF, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1998-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139627-A1 | Heterocyclic amide and imine derivatives, processes for their preparation, compositions comprising them and their use as pesticides | ACHE, DDT, PIR | ALDH1A1 1482/4885EPHX1 994/4885CYP1A2 12/4885 |
| US-20080097099-A1 | Heterocyclic amide and imine derivatives, processes for their preparation, compositions comprising them and their use as pesticides | ACHE, DDT, PIR | ALDH1A1 1101/4885EPHX1 887/4885CYP1A2 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.