Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3921187 | 1.00 | LCK (0.44) | LCKFYNBACE1NFE2L2KDM1A | |
| SCHEMBL4231864 | 0.90 | BACE1 (0.45) | BACE1NFE2L2KDM1AKDM4EALDH1A1 | |
| SCHEMBL4231859 | 0.90 | BACE1 (0.45) | BACE1NFE2L2KDM1AKDM4EALDH1A1 | |
| SCHEMBL3910995 | 0.83 | KDM4E (0.52) | LCKFYNBACE1NFE2L2KDM1A | |
| SCHEMBL3910992 | 0.83 | KDM4E (0.52) | LCKFYNBACE1NFE2L2KDM1A | |
| SCHEMBL25283139 | 0.77 | APP (0.55) | NFE2L2PTPN2PTPN1PTPN6KDM4E | |
| SCHEMBL3920813 | 0.77 | ALDH1A1 (0.51) | NFE2L2KDM4EALDH1A1HPGDESR1 | |
| SCHEMBL3920819 | 0.77 | ALDH1A1 (0.51) | NFE2L2KDM4EALDH1A1HPGDESR1 | |
| SCHEMBL26564790 | 0.77 | APP (0.55) | NFE2L2PTPN2PTPN1PTPN6KDM4E | |
| SCHEMBL29318569 | 0.76 | KDM4E (0.60) | BACE1KDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024350-B1 | PIPERIDINE DERIVATIVES AS HUMAN PAPILLOMA VIRUS INHIBITORS | ANACONDA PHARMA (FR) | 2013-09-18 | — | — | EP | disclosed |
| EP-2024350-A1 | PIPERIDINE DERIVATIVES AS HUMAN PAPILLOMA VIRUS INHIBITORS | Anaconda Pharma (FR) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007135106-A1 | PIPERIDINE DERIVATIVES AS HUMAN PAPILLOMA VIRUS INHIBITORS | ANACONDA PHARMA (FR) | 2007-11-29 | — | — | WO | disclosed |