Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.49 |
| ▸ | CES1 | P23141 | 3/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3921182 | 1.00 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2ACES2 | |
| SCHEMBL12693571 | 1.00 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2ACES2 | |
| SCHEMBL7451708 | 0.84 | EP300 (0.64) | CES2CES1EP300TDP1FAAH | |
| SCHEMBL11560694 | 0.84 | EP300 (0.64) | CES2CES1EP300TDP1FAAH | |
| SCHEMBL11723691 | 0.83 | MAPT (0.59) | MAPTALDH1A1MEN1KMT2ACES2 | |
| SCHEMBL995359 | 0.83 | MAPT (0.59) | MAPTALDH1A1MEN1KMT2ACES2 | |
| Ammonia Solution, Strong SCHEMBL28224094 | 0.81 | EP300 (0.59) | ALDH1A1CES2CES1EP300FAAH | |
| SCHEMBL11439397 | 0.81 | EP300 (0.60) | MAPTALDH1A1MEN1KMT2AEP300 | |
| SCHEMBL4914440 | 0.81 | EP300 (0.60) | MAPTALDH1A1MEN1KMT2AEP300 | |
| SCHEMBL10788834 | 0.81 | EP300 (0.60) | MAPTALDH1A1MEN1KMT2AEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080305066-A1 | 2-C-Substituted Propane-1,3-Dicarbonyl Compounds and Their Use in Neutralising Malodour | GIVAUDAN SA (CH) | 2008-12-11 | — | — | US | claimed |
| EP-1838278-A1 | 2-C-SUBSTITUTED PROPANE-1,3-DICARBONYL COMPOUNDS AND THEIR USE IN NEUTRALISING MALODOUR | Givaudan SA (CH) | 2007-10-03 | — | — | EP | claimed |
| WO-2006076821-A1 | 2 -C-SUBSTITUTED PROPANE-1, 3 -DICARBONYL COMPOUNDS AND THEIR USE IN NEUTRALISING MALODOUR | GIVAUDAN SA (CH) | 2006-07-27 | — | — | WO | claimed |
| US-9585362-B2 | Fragrance compounds | GIVAUDAN S.A. (CH) | 2017-03-07 | — | — | US | disclosed |
| US-20160286753-A1 | FRAGRANCE COMPOUNDS | GIVAUDAN SA (CH) | 2016-10-06 | — | — | US | disclosed |
| US-9447364-B2 | Fragrance compounds | GIVAUDAN S.A. (CH) | 2016-09-20 | — | — | US | disclosed |
| US-20150247109-A1 | FRAGRANCE COMPOUNDS | Givaudan, S.A. (CH) | 2015-09-03 | — | — | US | disclosed |
| US-9057041-B2 | Fragrance compounds | Givaudan, S.A. (CH) | 2015-06-16 | — | — | US | disclosed |
| US-20140031270-A1 | Fragrance Compounds | GIVAUDAN S.A. (CH) | 2014-01-30 | — | — | US | disclosed |
| US-8575386-B2 | Fragrance compounds | GIVAUDAN S.A. (CH) | 2013-11-05 | — | — | US | disclosed |
| EP-2032516-B1 | FRAGRANCE COMPOUNDS | GIVAUDAN SA (CH) | 2012-09-26 | — | — | EP | disclosed |
| US-20090202464-A1 | Fragrance Compounds | GIVAUDAN S.A. (CH) | 2009-08-13 | — | — | US | disclosed |
| EP-2032516-A1 | FRAGRANCE COMPOUNDS | Givaudan SA (CH) | 2009-03-11 | — | — | EP | disclosed |
| US-20080305066-A1 | 2-C-Substituted Propane-1,3-Dicarbonyl Compounds and Their Use in Neutralising Malodour | GIVAUDAN SA (CH) | 2008-12-11 | — | — | US | disclosed |
| WO-2007143873-A1 | FRAGRANCE COMPOUNDS | GIVAUDAN SA (CH) | 2007-12-21 | — | — | WO | disclosed |
| EP-1838278-A1 | 2-C-SUBSTITUTED PROPANE-1,3-DICARBONYL COMPOUNDS AND THEIR USE IN NEUTRALISING MALODOUR | Givaudan SA (CH) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006076821-A1 | 2 -C-SUBSTITUTED PROPANE-1, 3 -DICARBONYL COMPOUNDS AND THEIR USE IN NEUTRALISING MALODOUR | GIVAUDAN SA (CH) | 2006-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090202464-A1 | Fragrance Compounds | OR10J3, OR51E2, TAS2R5 | MAPT 4604/4885ALDH1A1 477/4885MEN1 2862/4885 |
| US-20080305066-A1 | 2-C-Substituted Propane-1,3-Dicarbonyl Compounds and Their Use in Neutralising Malodour | TYR, MAL2, ACMSD | MAPT 3095/4885ALDH1A1 152/4885MEN1 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.