SCHEMBL3921701

SCHEMBL3921701

N#CCCO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc21

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA3 P0DMS8 4/20 0.67
▸ ADORA1 P30542 2/20 0.67
▸ DPP4 P27487 1/20 0.67
▸ MEN1 O00255 1/20 0.67
▸ SLC28A1 O00337 1/20 0.67
▸ MAP3K7 O43318 1/20 0.67
▸ SLC28A2 O43868 1/20 0.67
▸ GAPDH P04406 1/20 0.67
▸ MAPK1 P28482 1/20 0.67
▸ ADORA2A P29274 1/20 0.67
▸ ADORA2B P29275 1/20 0.67
▸ STAT6 P42226 1/20 0.67
▸ PI4KA P42356 1/20 0.67
▸ KMT2A Q03164 1/20 0.67
▸ SMN1; SMN2 Q16637 1/20 0.67
▸ PI4K2B Q8TCG2 1/20 0.67
▸ DOT1L Q8TEK3 1/20 0.67
▸ SLC29A1 Q99808 1/20 0.67
▸ PI4K2A Q9BTU6 1/20 0.67
▸ SLC28A3 Q9HAS3 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13715739 1.00 ADORA3 (0.67) ADORA3ADORA1DPP4MEN1SLC28A1
SCHEMBL13743975 1.00 ADORA3 (0.67) ADORA3ADORA1DPP4MEN1SLC28A1
SCHEMBL24371378 0.90 ADORA3 (0.67) ADORA3ADORA1DPP4MEN1SLC28A1
SCHEMBL14424485 0.89 ADORA3 (0.73) ADORA3ADORA1DPP4MEN1SLC28A1
SCHEMBL7611755 0.89 ADORA3 (0.73) ADORA3ADORA1DPP4MEN1SLC28A1
SCHEMBL16174422 0.89 ADORA3 (0.73) ADORA3ADORA1DPP4MEN1SLC28A1
SCHEMBL7611746 0.89 ADORA3 (0.73) ADORA3ADORA1DPP4MEN1SLC28A1
SCHEMBL16243296 0.88 ADORA3 (0.72) ADORA3ADORA1DPP4MEN1SLC28A1
SCHEMBL28991005 0.88 ADORA3 (0.72) ADORA3ADORA1DPP4MEN1SLC28A1
SCHEMBL23928781 0.88 ADORA3 (0.72) ADORA3ADORA1DPP4MEN1SLC28A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569685-B2 Artificial RNAóS modified at the 2ó-hydroxyl group JAPAN SCIENCCE AND TECHNOLOGY AGENCY (JP) 2009-08-04 — — US claimed
US-20080021206-A1 Novel Artificial Rnaos Modified At The 2o-Hydroxyl Group JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2008-01-24 — — US claimed
EP-1726597-A1 NOVEL ARTIFICIAL RNAóS MODIFIED AT THE 2ó-HYDROXYL GROUP Japan Science and Technology Agency (JP) 2006-11-29 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080021206-A1 Novel Artificial Rnaos Modified At The 2o-Hydroxyl Group FBL, NSUN2, METTL16 ADORA3 519/4885ADORA1 793/4885DPP4 3884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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