Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356277 | 0.92 | SMN1; SMN2 (0.51) | FFAR1FFAR4GMNNALDH1A1LMNA | |
| SCHEMBL3927904 | 0.85 | ENPP2 (0.45) | FFAR1ALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL3885825 | 0.83 | CYP2D6 (0.39) | FFAR1L3MBTL1GMNNALDH1A1LMNA | |
| SCHEMBL11150979 | 0.75 | FFAR1 (0.51) | FFAR1FFAR4KEAP1L3MBTL1GMNN | |
| SCHEMBL69746 | 0.70 | FFAR1 (0.81) | FFAR1FFAR4KEAP1L3MBTL1LMNA | |
| SCHEMBL14732640 | 0.69 | FFAR1 (0.67) | FFAR1FFAR4KEAP1L3MBTL1GMNN | |
| SCHEMBL14312086 | 0.68 | SRD5A2 (0.54) | FFAR1FFAR4KEAP1ALDH1A1HRH3 | |
| Hydrochloric Acid SCHEMBL25264643 | 0.68 | FFAR1 (0.77) | FFAR1FFAR4KEAP1L3MBTL1LMNA | |
| SCHEMBL472281 | 0.68 | FFAR1 (0.59) | FFAR1FFAR4KEAP1L3MBTL1ALDH1A1 | |
| SCHEMBL1337387 | 0.68 | FFAR1 (0.69) | FFAR1FFAR4KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893196-A4 | DIARYLHYDANTOIN COMPOUNDS | UNIV CALIFORNIA (US) | 2009-03-18 | — | — | EP | disclosed |
| EP-1893196-A1 | DIARYLHYDANTOIN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006124118-A1 | DIARYLHYDANTOIN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-11-23 | — | — | WO | disclosed |